Meropen Injection 1 gm/vial contains Meropenem Trihydrate, a broad-spectrum carbapenem antibiotic used to treat serious and life-threatening bacterial infections. It is effective against Gram-positive, Gram-negative, and anaerobic bacteria, including strains resistant to other antibiotics.

This injectable formulation ensures rapid and accurate delivery, making it ideal for hospitalized patients with severe infections such as bacterial meningitis, complicated urinary tract infections, intra-abdominal infections, and hospital-acquired pneumonia.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Meropenem Trihydrate 1 gm

Mechanism of Action

Meropenem is a beta-lactam antibiotic that works by:

• Inhibiting bacterial cell wall synthesis

• Binding to penicillin-binding proteins (PBPs), causing bacterial cell lysis

• Effectively killing susceptible bacteria, including multi-drug resistant strains

Its broad-spectrum activity makes it suitable for severe and complicated infections requiring intravenous therapy.

Indications

Meropen Injection 1 gm/vial is indicated for:

• Complicated urinary tract infections (UTIs)

• Intra-abdominal infections, including peritonitis

• Bacterial meningitis

• Hospital-acquired pneumonia

• Severe sepsis or systemic infections caused by susceptible bacteria

Dosage and Administration

• Administer only under medical supervision

• Intravenous injection or infusion is recommended

• Typical adult dose: 1 gm every 8 hours, adjusted based on renal function and severity of infection

• Infuse over 15–30 minutes or as directed by the physician

• Dose adjustment may be necessary for patients with impaired kidney function

• Monitor clinical response and laboratory parameters during treatment

Precautions

• Use with caution in patients with known beta-lactam allergies

• Adjust dosage in renal impairment

• Monitor for superinfection or Clostridium difficile-associated diarrhea

• Avoid use for mild infections that can be treated with narrower-spectrum antibiotics

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Nausea, vomiting, or diarrhea

• Headache

• Injection site reactions

Serious but rare side effects may include:

• Severe allergic reactions (anaphylaxis)

• Seizures in high doses or in patients with renal impairment

• Blood disorders such as thrombocytopenia or neutropenia

• Severe diarrhea associated with Clostridium difficile

Seek immediate medical attention if severe symptoms occur.

Storage

• Store below 25°C

• Keep in a dry place, protected from light

• Keep out of reach of children

• Reconstituted solution should be used immediately or stored according to guidelines.