Meropen Injection 500 mg/vial contains Meropenem Trihydrate, a broad-spectrum carbapenem antibiotic used for the treatment of serious bacterial infections. It is highly effective against Gram-positive, Gram-negative, and anaerobic bacteria, including strains resistant to other antibiotics.

Meropen is commonly prescribed for complicated urinary tract infections, intra-abdominal infections, bacterial meningitis, and hospital-acquired pneumonia. Its injectable formulation ensures rapid and precise delivery, making it ideal for hospitalized patients and severe infections requiring intravenous therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Meropenem Trihydrate 500 mg

Mechanism of Action

Meropenem is a beta-lactam antibiotic that works by:

• Inhibiting bacterial cell wall synthesis

• Binding to penicillin-binding proteins (PBPs), leading to cell lysis

• Effectively killing susceptible bacteria, including multi-drug resistant strains

Its broad-spectrum activity makes it suitable for treating life-threatening or complicated infections.

Indications

Meropen Injection 500 mg/vial is indicated for:

• Complicated urinary tract infections (UTIs)

• Intra-abdominal infections, including peritonitis

• Bacterial meningitis

• Hospital-acquired pneumonia

• Severe sepsis or systemic infections caused by susceptible bacteria

Dosage and Administration

• Administer only under the supervision of a qualified healthcare professional

• Intravenous injection or infusion is recommended

• Typical adult dose: 500 mg every 8 hours, adjusted based on renal function and severity of infection

• Infuse over 15–30 minutes or as prescribed

• Dose adjustments may be necessary in patients with impaired kidney function

• Monitor patient response and laboratory parameters during therapy

Precautions

• Use with caution in patients with allergies to beta-lactams

• Adjust dose in renal impairment

• Monitor for signs of superinfection with prolonged use

• Not recommended for mild infections that respond to narrower-spectrum antibiotics

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Nausea, vomiting, or diarrhea

• Headache

• Rash or injection site reactions

Rare but serious side effects may include:

• Severe allergic reactions (anaphylaxis)

• Seizures in high doses or patients with renal impairment

• Clostridium difficile-associated diarrhea

• Blood disorders (e.g., thrombocytopenia, neutropenia)

Seek immediate medical attention if severe symptoms occur.

Storage

• Store below 25°C

• Keep in a dry place, protected from light

• Keep out of reach of children

• Reconstituted solution should be used immediately or stored as per guidelines.