Milran Tablet 12.5 mg contains Milnacipran Hydrochloride, a serotonin and norepinephrine reuptake inhibitor (SNRI) used primarily in the management of fibromyalgia and depressive disorders. It helps improve mood, reduce pain perception, and enhance physical function in patients suffering from chronic pain conditions associated with central nervous system dysregulation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Milnacipran Hydrochloride 12.5 mg

Mechanism of Action

Milnacipran works by inhibiting the reuptake of two key neurotransmitters: serotonin and norepinephrine. Its actions include:

• Increasing serotonin levels to improve mood and emotional stability
• Increasing norepinephrine levels to enhance pain modulation pathways
• Reducing central pain sensitivity in fibromyalgia patients
• Improving energy levels and cognitive function in some patients

This dual action makes it effective in both pain and mood-related disorders.

Indications

Milran Tablet is indicated for:

• Fibromyalgia syndrome
• Major depressive disorder (as prescribed by a physician)
• Chronic musculoskeletal pain associated with central sensitization
• Fatigue and functional impairment related to fibromyalgia

Dosage and Administration

• Dosage should be determined by a physician and gradually adjusted
• Usually taken orally once or twice daily
• Can be taken with or without food
• It is recommended to start with a low dose and increase gradually to minimize side effects
• Do not stop abruptly without medical advice

Benefits

• Reduces widespread musculoskeletal pain
• Improves mood and emotional well-being
• Enhances energy and daily functioning
• Helps reduce fatigue associated with fibromyalgia
• Improves overall quality of life in chronic pain conditions

Possible Side Effects

Common side effects may include:

• Nausea
• Headache
• Dizziness
• Dry mouth
• Increased sweating
• Insomnia or sleep disturbance

Less common but serious effects may include increased blood pressure or mood changes.

Precautions

• Use cautiously in patients with hypertension or heart disease
• Monitor blood pressure regularly during treatment
• Not recommended for use in severe renal impairment
• Avoid abrupt discontinuation to prevent withdrawal symptoms
• Use during pregnancy or breastfeeding only if clearly needed

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Milnacipran may interact with:

• Other antidepressants (risk of serotonin syndrome)
• MAO inhibitors (contraindicated)
• Blood pressure medications
• CNS stimulants

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool, dry place
• Protect from moisture and light
• Keep out of reach of children.