Miptol Tablet contains Misoprostol 200 mcg, a synthetic prostaglandin E1 analog widely used in gastroenterology and obstetrics. Misoprostol works by protecting the stomach lining, reducing gastric acid secretion, and promoting uterine contractions, depending on its therapeutic use. Miptol is particularly effective in preventing NSAID-induced gastric ulcers, managing postpartum hemorrhage, and supporting medical termination of pregnancy under medical supervision.

Miptol 200 mcg is a fast-acting oral formulation, offering precise dosing and predictable pharmacological effects. Its multiple applications in gastrointestinal protection and reproductive health make it a versatile and essential medication in clinical practice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Miptol Tablet 200 mcg is indicated for:

• Prevention of NSAID-induced gastric and duodenal ulcers in patients requiring long-term NSAID therapy

• Medical termination of pregnancy in early gestation (under physician supervision)

• Management of postpartum hemorrhage to reduce bleeding after childbirth

• Cervical ripening and induction of labor in obstetric care

• Treatment of gastric erosions or gastritis associated with NSAID use

The indication depends on the patient’s medical condition and the prescribing physician’s evaluation.

Mechanism of Action

Misoprostol exerts its effects through two primary mechanisms:

1. Gastroprotective Action:

   • Stimulates production of mucus and bicarbonate in the stomach lining

   • Reduces gastric acid secretion, preventing damage from NSAIDs

   • Protects gastric and duodenal mucosa from erosion and ulcer formation

2. Uterotonic Action:

   • Binds to prostaglandin receptors in the uterus

   • Induces uterine contractions, leading to expulsion of uterine contents when used in abortion or labor induction

   • Reduces postpartum bleeding by enhancing uterine tone

These dual actions make Miptol both a protective and therapeutic agent depending on the clinical context.

Dosage and Administration

For NSAID-induced ulcer prevention:

• Adults: 200 mcg orally 2–4 times daily with meals, depending on risk factors

For medical termination of pregnancy (early gestation):

• Dosage and administration must follow strict medical guidelines and supervision

For postpartum hemorrhage:

• Administer as per obstetric protocol, usually 200–400 mcg orally or sublingually

Administration Guidelines:

• Swallow tablets whole with water

• Can be taken with or without food, though taking with meals reduces gastrointestinal discomfort

• Strict adherence to physician instructions is essential for reproductive use

Benefits of Miptol Tablet

• Prevents NSAID-related gastric ulcers and gastritis

• Protects gastrointestinal mucosa from acid-related damage

• Supports safe management of postpartum hemorrhage

• Facilitates medical termination of pregnancy when used under medical guidance

• Promotes uterine contractions for cervical ripening and labor induction

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Contraindicated in pregnancy except when used for medical abortion under supervision

• Use cautiously in patients with cardiovascular, hepatic, or renal impairment

• Avoid use in patients with known allergy to Misoprostol or prostaglandins

• Monitor for bleeding or gastrointestinal side effects during therapy

Side Effects

Common side effects include:

• Abdominal pain, nausea, diarrhea

• Flatulence or dyspepsia

• Headache

Rare but serious effects:

• Excessive uterine bleeding

• Allergic reactions (rash, itching, or anaphylaxis)

• Uterine rupture in labor induction if improperly used

Storage

• Store in a cool, dry place below 30°C

• Keep tablets in the original container, protected from light and moisture

• Keep out of reach of children