Nabumax Tablet 500 mg contains Nabumetone, a non-steroidal anti-inflammatory drug (NSAID) used for the management of pain and inflammation associated with musculoskeletal and joint disorders. It helps reduce swelling, stiffness, and pain, improving mobility and daily functioning in patients with chronic inflammatory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Nabumetone 500 mg
• Dosage Form: Oral tablet

Indications

Nabumax Tablet 500 mg is indicated for:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Musculoskeletal pain and inflammatory conditions
• Other painful inflammatory disorders as prescribed by a physician

Mechanism of Action

Nabumetone is a prodrug NSAID that is converted in the liver to its active metabolite. It works by:

• Inhibiting cyclooxygenase (COX) enzymes
• Reducing production of prostaglandins, the mediators of pain and inflammation
• Relieving pain, swelling, and joint stiffness

Its preferential COX-2 activity may provide improved gastrointestinal tolerability compared to some traditional NSAIDs.

Dosage and Administration

• Usual dose: 500 mg once or twice daily, as directed by a physician
• Should be taken with food to reduce stomach irritation
• Swallow whole with water
• Dosage may be adjusted based on severity of symptoms and patient response

Side Effects

Common side effects:

• Stomach upset or discomfort
• Nausea
• Headache
• Dizziness

Serious side effects:

• Gastrointestinal bleeding or ulceration
• Kidney function impairment
• Liver enzyme elevation
• Allergic reactions (rash, swelling)

Precautions and Warnings

• Use cautiously in patients with history of peptic ulcer or GI bleeding
• Avoid in severe renal or hepatic impairment
• Long-term use may increase cardiovascular risk
• Use lowest effective dose for the shortest duration
• Caution in elderly patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Increased risk of bleeding with anticoagulants (e.g., warfarin)
• Interaction with other NSAIDs or corticosteroids increases GI risk
• May reduce effectiveness of certain antihypertensive drugs
• Caution with diuretics and lithium

Storage Conditions

• Store below 25°C
• Protect from moisture and light
• Keep out of reach of children.