Neofloxin-D Eye Drop is a sterile ophthalmic preparation that combines Ciprofloxacin 0.3%, a broad-spectrum fluoroquinolone antibiotic, with Dexamethasone 0.1%, a potent corticosteroid. This dual-action formulation is designed to effectively manage bacterial eye infections associated with inflammation, providing both antimicrobial protection and rapid anti-inflammatory relief.

The antibiotic component, ciprofloxacin, works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial replication and survival. It is highly effective against a wide range of Gram-negative and Gram-positive bacteria, including many pathogens commonly responsible for ocular infections. Dexamethasone complements this action by suppressing inflammatory responses such as redness, swelling, pain, and irritation, thereby improving patient comfort and speeding recovery.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Neofloxin-D Eye Drop is indicated for the treatment of steroid-responsive inflammatory ocular conditions where bacterial infection or risk of infection exists, including:

• Bacterial conjunctivitis with inflammation

• Blepharitis and blepharoconjunctivitis

• Keratitis (non-viral)

• Post-operative ocular inflammation with risk of infection

• Anterior segment inflammation associated with bacterial infection

Dosage and Administration

The dosage should be determined by a qualified healthcare professional based on the severity of the condition.

• Usually, 1–2 drops are instilled into the affected eye(s) every 4–6 hours

• In severe infections, dosing frequency may be increased initially and then reduced gradually

• Shake well before use

• Avoid touching the dropper tip to prevent contamination

Treatment duration should be limited to the shortest effective period to reduce the risk of steroid-related adverse effects.

Pharmacological Benefits

• Broad-spectrum antibacterial coverage

• Rapid reduction of ocular inflammation and discomfort

• Improved healing and patient compliance

• Suitable for mixed infective-inflammatory eye conditions

Ciprofloxacin achieves high concentrations in ocular tissues, while dexamethasone effectively controls inflammatory mediators, making this combination particularly useful in acute and post-surgical settings.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Prolonged use may increase the risk of secondary infections, glaucoma, or cataract formation

• Not indicated for viral, fungal, or tuberculous eye infections

• Use with caution in patients with a history of hypersensitivity to fluoroquinolones or corticosteroids

• Contact lenses should be removed before instillation and avoided during treatment

• Use in children, pregnant, or breastfeeding women only if clearly prescribed by a physician

Adverse Effects

Common side effects may include:

• Temporary burning or stinging sensation

• Eye irritation or discomfort

• Blurred vision immediately after application

Rare but serious effects with prolonged use may include increased intraocular pressure or delayed wound healing.

Storage

• Store below 30°C

• Protect from light

• Do not freeze

• Keep the bottle tightly closed when not in use

• Discard the bottle 4 weeks after opening

Presentation

Neofloxin-D Eye Drop is supplied in a sterile, easy-to-use ophthalmic dropper bottle, ensuring accurate dosing and safe administration.