Nitrofur SR Capsule 100 mg contains Nitrofurantoin, a long-acting antibiotic specifically designed to treat urinary tract infections (UTIs). This sustained-release (SR) formulation ensures prolonged drug release, maintaining effective antibiotic levels in the urinary tract for extended periods. Nitrofurantoin works by inhibiting bacterial enzymes critical for DNA, RNA, and protein synthesis, effectively eliminating the infection-causing bacteria.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nitrofur SR Capsule 100 mg is indicated for:

• Treatment of acute urinary tract infections (UTIs)
• Prevention of recurrent UTIs
• Infections caused by susceptible bacteria, including Escherichia coli and Staphylococcus saprophyticus

Mechanism of Action

Nitrofurantoin acts by interfering with bacterial enzyme systems essential for the synthesis of DNA, RNA, and proteins. This bactericidal activity effectively kills susceptible bacteria. Being rapidly excreted in urine, it ensures high concentrations in the urinary tract, targeting the infection site directly.

Dosage and Administration

• Usually administered as 100 mg once or twice daily, as prescribed by a physician
• Swallow the capsule whole with water; do not crush or chew
• Take with food or milk to reduce stomach irritation
• Complete the full course of therapy even if symptoms improve

Benefits

• Sustained-release formulation for prolonged action
• Convenient once or twice-daily dosing
• Effective treatment and prevention of UTIs
• Reduces bacterial recurrence and promotes urinary tract health
• Well-tolerated in adults

Possible Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or mild stomach upset
• Loss of appetite

Rare but serious side effects:

• Allergic reactions (rash, itching, swelling)
• Liver function abnormalities
• Pulmonary reactions (shortness of breath, cough)

Discontinue and consult a healthcare provider if severe symptoms occur.

Precautions and Warnings

• Not recommended in patients with severe kidney impairment
• Use cautiously in elderly patients
• Avoid during late pregnancy due to risk of hemolytic anemia in newborns
• Take with food or milk to reduce gastrointestinal irritation
• Do not use for systemic infections outside the urinary tract

Drug Interactions

Nitrofurantoin may interact with:

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

• Antacids containing magnesium trisilicate (may reduce absorption)
• Certain urinary acidifiers
• Other nephrotoxic medications

Always inform your healthcare provider about all medications being taken.

Storage

• Store below 25°C in a dry, cool place
• Protect from light and moisture
• Keep the capsule in its original container until use
• Keep out of reach of children.