Nystat Tablet 500,000 Unit contains Nystatin, an effective antifungal medication used to treat infections caused by Candida species, particularly in the oral cavity and gastrointestinal tract. Nystatin belongs to the polyene class of antifungal agents and works by disrupting the fungal cell membrane, leading to cell death. It is commonly prescribed for the treatment of oral thrush, gastrointestinal candidiasis, and other fungal infections caused by susceptible strains of yeast.

Nystatin has a broad antifungal spectrum and is minimally absorbed from the gastrointestinal tract, which makes it highly effective for localized infections in the mouth and digestive system with limited systemic side effects. Its targeted action helps eliminate fungal infections while maintaining the natural balance of gut flora.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nystat Tablet 500,000 Unit is indicated for:

• Oral thrush (candidiasis of the mouth and throat)

• Gastrointestinal candidiasis

• Fungal infections in the digestive tract

• Prevention of fungal overgrowth in immunocompromised patients (under medical supervision)

• Supportive treatment in patients using broad-spectrum antibiotics, which can predispose to Candida overgrowth

Mechanism of Action

Nystatin exerts its antifungal effect by:

• Binding to ergosterol, an essential component of fungal cell membranes.

• Creating pores in the fungal cell membrane, leading to leakage of cellular contents.

• Causing fungal cell death while sparing human cells, as ergosterol is absent in mammalian membranes.

This mechanism makes Nystatin highly effective against Candida species without significant systemic toxicity, as it is poorly absorbed when taken orally.

Dosage and Administration

The dosage of Nystat Tablet 500,000 Unit depends on the age, severity of infection, and physician recommendation:

• Adults: Typically 1 tablet taken 3–4 times daily after meals.

• Swallow the tablet whole with water; do not chew unless directed by a physician.

• Complete the full course of therapy, even if symptoms improve earlier, to prevent recurrence.

For pediatric patients or infants, dose adjustment may be required, and administration should be guided by a healthcare professional.

Precautions and Warnings

• Consult a physician before use in cases of liver disease or other chronic conditions.

• Use with caution in patients with known hypersensitivity to Nystatin or other polyene antifungals.

• Avoid using Nystatin for systemic fungal infections, as oral absorption is minimal.

• Inform your doctor if you are pregnant or breastfeeding before starting therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Nystatin is generally well-tolerated. Mild side effects may include:

• Nausea or vomiting

• Diarrhea

• Stomach discomfort

• Mild skin rash or itching (rare)

Serious side effects are extremely rare due to minimal systemic absorption. Seek medical attention if severe allergic reactions occur.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Nystat Tablet 500,000 Unit is an effective antifungal medication for the treatment and prevention of oral and gastrointestinal Candida infections, offering a safe and reliable option under medical supervision.