Odacef DS Suspension 200 mg/5 ml contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic formulated as a double-strength (DS) oral suspension. This high-potency suspension is designed to treat moderate to severe bacterial infections in patients who require flexible dosing, particularly children and adults who have difficulty swallowing tablets or capsules. Its convenient liquid formulation ensures accurate dose measurement and improved compliance while delivering broad-spectrum antibacterial activity.

Cefixime Trihydrate acts by interfering with bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting peptidoglycan cross-linking. This weakens the bacterial cell wall, ultimately leading to bacterial lysis and death. As a third-generation cephalosporin, Cefixime demonstrates enhanced activity against Gram-negative bacteria while maintaining efficacy against selected Gram-positive organisms, making it suitable for a wide variety of infections.

Odacef DS Suspension 200 mg/5 ml is particularly useful for respiratory tract infections, urinary tract infections, ear infections, throat infections, and skin and soft tissue infections caused by susceptible bacteria. Its palatable formulation and double-strength concentration allow for fewer doses and easier administration, particularly in pediatric patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Active Ingredient – Cefixime Trihydrate 200 mg/5 ml: Broad-spectrum, third-generation cephalosporin antibiotic.

• Double Strength Suspension: Higher concentration for more convenient dosing.

• Bactericidal Action: Inhibits bacterial cell wall synthesis to effectively eradicate infections.

• Broad-Spectrum Coverage: Effective against respiratory, urinary, ear, throat, and skin infections.

• Pediatric and Adult Friendly: Easy-to-administer oral suspension with accurate dosing.

Indications

Odacef DS Suspension 200 mg/5 ml is indicated for the treatment of:

• Acute and chronic respiratory tract infections (bronchitis, pneumonia)

• Urinary tract infections (cystitis, urethritis)

• Otitis media (middle ear infections)

• Pharyngitis and tonsillitis

• Skin and soft tissue infections caused by susceptible bacteria

The suspension should be used under medical supervision, with doses adjusted based on age, weight, and infection severity, ensuring safe and effective therapy.

Mechanism of Action

Cefixime Trihydrate belongs to the beta-lactam class of antibiotics. It binds to PBPs in the bacterial cell wall, preventing the final cross-linking of peptidoglycan, which is essential for maintaining bacterial wall strength. This disruption causes structural instability, bacterial lysis, and eventual eradication of the infection.

As a third-generation cephalosporin, Cefixime offers enhanced Gram-negative activity while retaining action against certain Gram-positive bacteria, providing a broad spectrum of antibacterial coverage.

Dosage and Administration

• Shake the bottle well before each use to ensure even suspension.

• Pediatric dose: Typically 8 mg/kg/day, divided into one or two doses, or as directed by a physician.

• Adults or older children may use DS suspension if unable to swallow capsules; dosage should be prescribed by a healthcare professional.

• Measure doses accurately using a calibrated measuring spoon or oral syringe.

• Complete the full prescribed course, even if symptoms improve, to prevent recurrence and reduce the risk of antibiotic resistance.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Odacef DS Suspension 200 mg/5 ml is generally well tolerated. Common side effects may include mild gastrointestinal disturbances such as diarrhea, nausea, or abdominal discomfort. Allergic reactions, including rash, itching, or, rarely, anaphylaxis, may occur in sensitive individuals.

Avoid use in patients with known hypersensitivity to cephalosporins or penicillins. Dose adjustment may be required in patients with renal impairment.

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

With proper administration, Odacef DS Suspension 200 mg/5 ml provides safe, effective, and convenient treatment for bacterial infections, ensuring rapid symptom relief and supporting full recovery.