Olopan 600 mcg/spray contains Olopatadine, a well-established antiallergic agent used in ophthalmology. It is specially formulated to relieve ocular symptoms associated with allergic conjunctivitis, particularly eye itching. Olopatadine works by targeting the allergic response at its source, offering effective and long-lasting symptom control with minimal systemic exposure when used as directed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Olopan 600 mcg/spray is indicated for the treatment of:

• Ocular itching associated with allergic conjunctivitis

Therapeutic Class

• Ophthalmic Non-Steroid Drugs

Pharmacology

Olopatadine acts as a dual-action antiallergic agent. It inhibits the release of histamine from mast cells and selectively antagonizes histamine H1 receptors. Through this mechanism, it suppresses both in vivo and in vitro type-1 immediate hypersensitivity reactions. Olopatadine also inhibits histamine-induced effects on human conjunctival epithelial cells.
Importantly, olopatadine shows no significant activity on alpha-adrenergic, dopaminergic, or muscarinic (type 1 and 2) receptors. After topical ocular administration, systemic absorption is minimal, reducing the likelihood of systemic side effects.

Dosage and Administration

Dosage should be followed exactly as prescribed by a physician:

• 0.1% Sterile Eye Drops: One drop in each affected eye twice daily at intervals of 6–8 hours

• 0.2% Sterile Eye Drops: One drop in the affected eye once daily

• 0.7% Sterile Eye Drops: One drop in each affected eye once daily

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Concomitant use with central nervous system depressants may result in additive CNS depression.

Contraindications

Olopan 600 mcg/spray ophthalmic solution is contraindicated in patients with:

• Known hypersensitivity to Olopatadine or any component of the formulation

Side Effects

Headache has been reported in approximately 7% of patients. Other adverse effects reported in fewer than 5% of patients include:

• Asthenia

• Blurred vision

• Burning or stinging sensation

• Dry eye

• Foreign body sensation

• Hyperemia

• Hypersensitivity reactions

• Keratitis

• Lid edema

• Nausea

• Pharyngitis

• Pruritus

• Rhinitis

• Sinusitis

• Taste perversion

Pregnancy and Lactation

There are no adequate and well-controlled studies in pregnant women. Olopan 600 mcg/spray should be used during pregnancy only if the potential benefit justifies the possible risk to the fetus.
It is unknown whether olopatadine is excreted in human breast milk following topical ocular administration. Caution is advised when administering to nursing mothers.

Precautions and Warnings

• Not intended for treatment of contact lens-related irritation

• Soft contact lenses should be removed prior to instillation and may be reinserted after at least 10 minutes

Overdose

Symptoms: Drowsiness in adults; in children, initial agitation and restlessness followed by drowsiness
Management: Symptomatic and supportive treatment

Storage Conditions

• Store below 30°C in a cool and dry place

• Protect from light

• Keep out of reach of children

• Avoid touching the dropper tip to any surface

• Discard the product 30 days after first opening

Use in Special Populations

Geriatric Use: No significant differences in safety or effectiveness have been observed in elderly patients compared to younger adults.