Omari Tablet 12.5 mg contains Omarigliptin, a modern oral antidiabetic medication classified as a Dipeptidyl Peptidase-4 (DPP-4) inhibitor. It is specifically designed for the management of type 2 diabetes mellitus, helping patients maintain optimal blood glucose levels when diet and exercise alone are insufficient. Omarigliptin works by enhancing the body’s natural incretin system, which regulates insulin secretion and glucose metabolism.

A unique advantage of Omarigliptin is its once-weekly dosing, providing convenience and improving adherence compared to daily antidiabetic medications. This long-acting DPP-4 inhibitor helps reduce fasting and postprandial blood sugar while minimizing the risk of hypoglycemia when used appropriately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Supports glycemic control in type 2 diabetes mellitus

• Reduces fasting and postprandial blood glucose levels

• Enhances natural insulin secretion in response to meals

• Inhibits excessive glucagon release, improving glucose metabolism

• Once-weekly dosing for improved convenience and adherence

• Weight-neutral effect, with minimal risk of hypoglycemia when used alone

Mechanism of Action

Omarigliptin, the active ingredient in Omari Tablet, acts as a DPP-4 enzyme inhibitor:

1. DPP-4 Inhibition: Prevents the breakdown of incretin hormones, including GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide).

2. Enhanced Insulin Secretion: Increases insulin release from the pancreas in response to meals, helping lower postprandial blood glucose.

3. Reduced Glucagon Secretion: Lowers the release of glucagon, a hormone that raises blood glucose, particularly during fasting.

4. Improved Glycemic Control: By regulating insulin and glucagon levels, Omarigliptin helps maintain stable blood glucose throughout the day and night.

Indications

Omari Tablet 12.5 mg is indicated for:

• Adults with type 2 diabetes mellitus to improve glycemic control

• Patients inadequately controlled by diet and exercise alone

• Adjunct therapy with other oral antidiabetic agents or insulin when necessary

• Suitable for patients seeking a once-weekly antidiabetic regimen for convenience

Dosage and Administration

• Recommended dose: 12.5 mg once weekly, orally, as directed by a healthcare professional.

• Can be taken with or without food, at the same time each week for consistency.

• Continue diet and exercise programs as advised by a physician to optimize blood glucose control.

• Regular monitoring of blood glucose levels is recommended to assess effectiveness and adjust therapy if necessary.

Precautions and Warnings

• Not indicated for type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.

• Use with caution in patients with renal impairment; dose adjustment may be required.

• Inform the physician of all medications being taken to avoid potential drug interactions.

• Discontinue and seek medical attention if signs of allergic reaction or severe side effects occur.

Possible Side Effects

Omari Tablet is generally well-tolerated. Mild side effects may include:

• Nasopharyngitis (common cold)

• Headache

• Gastrointestinal discomfort such as nausea

• Rare cases of hypersensitivity reactions

Hypoglycemia is uncommon when used as monotherapy but may occur when combined with other antidiabetic agents such as sulfonylureas or insulin.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a dry, cool place, protected from light and moisture. Keep out of reach of children.

Omari Tablet 12.5 mg offers effective once-weekly glycemic control in type 2 diabetes, supporting stable blood glucose levels, enhancing insulin secretion, and providing convenience for patients seeking a long-acting antidiabetic solution.