Orin Tablet 10 mg contains Loratadine, a second-generation antihistamine used for the relief of allergic conditions in adults and children over 2 years of age. Loratadine is a selective H1 receptor antagonist, which works by blocking the action of histamine, a chemical mediator responsible for allergy symptoms such as sneezing, itching, runny nose, watery eyes, and hives.

Unlike first-generation antihistamines, Orin Tablet 10 mg is non-sedating, making it suitable for daily use without causing drowsiness. It is effective in managing both seasonal and perennial allergic conditions, providing rapid and long-lasting relief from discomfort associated with allergies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Provides relief from allergic rhinitis (seasonal and perennial)

• Reduces symptoms of sneezing, nasal congestion, runny nose, and itchy eyes

• Effective in managing chronic idiopathic urticaria (hives) and skin allergies

• Non-drowsy formulation, allowing normal daily activities

• Long-lasting effect with once-daily dosing

• Suitable for adults and children over 2 years of age

Mechanism of Action

Loratadine, the active ingredient in Orin Tablet 10 mg, acts as a selective H1 receptor antagonist:

1. Histamine Blockade:

   • Histamine is released during allergic reactions and binds to H1 receptors on target tissues, causing symptoms like itching, swelling, and vasodilation.

   • Loratadine blocks H1 receptors, preventing histamine from exerting its effects.

2. Anti-Allergic Effect:

   • Reduces nasal and ocular allergy symptoms, including sneezing, nasal congestion, runny nose, and watery or itchy eyes.

   • Controls skin manifestations such as hives, redness, and itching in chronic urticaria.

3. Non-Sedating Property:

   • Unlike first-generation antihistamines, Loratadine does not cross the blood-brain barrier significantly, avoiding sedation and drowsiness.

Indications

Orin Tablet 10 mg is indicated for:

• Seasonal allergic rhinitis (hay fever)

• Perennial allergic rhinitis caused by dust, pollen, or pet dander

• Relief of symptoms associated with chronic idiopathic urticaria (hives)

• Skin allergies causing itching and redness

Dosage and Administration

• Adults and children over 12 years: 10 mg once daily

• Children 2–12 years: Consult a physician for age-appropriate dosing (usually 5 mg once daily)

• Can be taken with or without food

• Swallow the tablet whole with water; do not crush or chew

Precautions and Warnings

• Consult a doctor before use in patients with liver or kidney impairment.

• Not recommended for children under 2 years of age.

• Avoid combining with other antihistamines without physician guidance.

• Though non-sedating, a small number of patients may experience mild drowsiness.

• Pregnant and breastfeeding women should use only under medical supervision.

Possible Side Effects

Orin Tablet 10 mg is generally well-tolerated. Mild side effects may include:

• Headache

• Dry mouth

• Fatigue

• Mild gastrointestinal discomfort

Serious side effects are rare but may include allergic reactions such as rash, swelling, or difficulty breathing. Seek immediate medical attention if these occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a dry, cool place, protected from light and moisture. Keep out of reach of children.

Orin Tablet 10 mg provides effective, non-sedating relief from allergic symptoms, helping patients maintain normal daily activities while managing seasonal or chronic allergies safely and conveniently.