Pegalin ER Tablet 165 mg contains Pregabalin in an extended-release formulation designed to provide consistent and long-lasting therapeutic effects throughout the day. It is used for the management of neuropathic pain, epilepsy, and generalized anxiety disorder. The extended-release technology ensures gradual drug release, maintaining stable blood levels and improving overall symptom control with once-daily dosing convenience.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 165 mg (Extended Release)

Indications

Pegalin ER Tablet is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Chronic nerve pain requiring sustained treatment

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, leading to decreased neuronal excitability. The extended-release formulation provides gradual absorption and prolonged plasma concentration, ensuring continuous symptom relief.

Dosage and Administration

• Usually taken once daily or as directed by a physician.
• Swallow whole with water; do not crush, chew, or break the tablet.
• Take at the same time each day for consistent effect.
• Dosage is individualized based on medical condition and response.
• Do not stop abruptly without medical supervision.

Benefits

• Long-lasting relief from neuropathic pain
• Once-daily dosing improves patient compliance
• Stable and sustained drug release
• Helps reduce burning, tingling, and nerve pain sensations
• Supports management of anxiety and seizure disorders
• Improves sleep and quality of life

Side Effects

Pegalin ER Tablet may cause:

• Drowsiness or dizziness
• Blurred vision
• Weight gain
• Fatigue
• Dry mouth
• Peripheral edema (rare)

Side effects are usually mild and improve with continued therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use with caution in patients with renal impairment (dose adjustment required).
• Do not crush or chew due to extended-release formulation.
• Avoid alcohol during treatment.
• Do not discontinue abruptly; gradual tapering may be required.
• Use only under medical supervision.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.