PegFilgrast Injection 6 mg/0.6 ml contains Pegfilgrastim, a long-acting form of granulocyte colony-stimulating factor (G-CSF). It is used to reduce the risk of infection in patients undergoing chemotherapy by increasing the production of neutrophils (a type of white blood cell). This helps strengthen the immune system and lowers the chance of chemotherapy-induced neutropenia.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Pegfilgrastim (Pegylated Filgrastim)
• Strength: 6 mg per 0.6 ml

Mechanism of Action

Pegfilgrastim stimulates the bone marrow to produce and release neutrophils into the bloodstream. These white blood cells play a key role in fighting infections. The pegylated form allows the drug to stay active in the body longer, providing sustained stimulation of neutrophil production after chemotherapy.

Indications

PegFilgrast Injection is indicated for:

• Prevention of febrile neutropenia in patients receiving myelosuppressive chemotherapy
• Reduction of infection risk during cancer treatment
• Supportive care in oncology patients with low white blood cell counts
• Patients at high risk of chemotherapy-induced neutropenia

Dosage and Administration

• Administered as a subcutaneous injection by healthcare professionals
• Usually given once per chemotherapy cycle (24 hours after chemotherapy)
• Dosage is standardized but may be adjusted by oncologists
• Not intended for self-administration

Benefits

• Increases white blood cell production
• Reduces risk of serious infections during chemotherapy
• Shortens duration of neutropenia
• Improves ability to continue cancer treatment on schedule
• Long-acting single-dose convenience

Possible Side Effects

Common side effects may include:

• Bone pain
• Headache
• Muscle pain
• Fatigue
• Injection site reactions

Rare but serious side effects may include spleen enlargement or rupture and allergic reactions.

Precautions and Warnings

• Must be used under oncology supervision
• Monitor for signs of splenic rupture (left upper abdominal pain, shoulder pain)
• Not recommended in patients with certain blood disorders unless prescribed
• Use with caution in patients with sickle cell disease
• Inform doctor about all ongoing treatments

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a refrigerator (2°C to 8°C)
• Do not freeze
• Protect from light
• Keep out of reach of children

Conclusion

PegFilgrast Injection 6 mg/0.6 ml (Pegfilgrastim) is a long-acting supportive cancer therapy used to reduce infection risk in patients undergoing chemotherapy. It enhances white blood cell production and helps maintain treatment safety under medical supervision.