Probis Tablet 1.25 mg contains Bisoprolol Fumarate, a cardioselective beta-1 adrenergic receptor blocker used to manage cardiovascular conditions such as hypertension, angina pectoris, and chronic heart failure. This low-dose formulation is ideal for initiating therapy, especially in patients who are sensitive to beta-blockers or require gradual dose titration. Bisoprolol reduces heart rate, myocardial contractility, and blood pressure, helping decrease the heart’s workload and oxygen demand while improving overall cardiac function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Bisoprolol Fumarate: 1.25 mg

Mechanism of Action

Bisoprolol selectively blocks beta-1 adrenergic receptors in the heart:

• Decreases heart rate and cardiac output
• Lowers blood pressure by reducing sympathetic stimulation
• Reduces myocardial oxygen demand, preventing angina attacks
• Improves left ventricular function in chronic heart failure

Its cardioselectivity reduces unwanted effects on the lungs and peripheral blood vessels compared to non-selective beta-blockers.

Indications

Probis Tablet 1.25 mg is indicated for:

• Initial therapy in hypertension (high blood pressure)
• Management of angina pectoris (chest pain due to heart disease)
• Chronic heart failure as part of a stepwise treatment plan
• Patients requiring gradual titration to higher beta-blocker doses

Dosage and Administration

• Take orally as prescribed by a healthcare professional.
• Typical starting dose: 1 tablet once daily; may be increased gradually based on response.
• Swallow the tablet with water, preferably at the same time each day.
• Do not stop therapy abruptly; consult your doctor before discontinuation.

Benefits

• Safe initiation of beta-blocker therapy for sensitive patients
• Reduces high blood pressure effectively
• Controls angina symptoms by decreasing heart workload
• Supports long-term management of chronic heart failure
• Facilitates gradual titration to higher doses as needed

Side Effects

Common side effects may include:

• Fatigue or dizziness
• Slow heart rate (bradycardia)
• Cold hands and feet
• Mild gastrointestinal upset

Rare but serious side effects:

• Severe hypotension
• Worsening heart failure
• Allergic reactions

Seek immediate medical attention if severe dizziness, fainting, swelling, or difficulty breathing occurs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use with caution in patients with asthma, diabetes, or severe heart disease.
• Regularly monitor blood pressure and heart rate during therapy.
• Inform your doctor if pregnant, breastfeeding, or taking other medications.
• Avoid abrupt discontinuation to prevent rebound hypertension or angina.
• Keep out of reach of children.

Storage

• Store in a cool, dry place below 30°C
• Protect from light and moisture
• Keep the container tightly closed.