Progut-N Tablet is a combination of Naproxen Sodium, a non-steroidal anti-inflammatory drug (NSAID), and Esomeprazole Magnesium, a proton pump inhibitor (PPI). It is used for the management of pain and inflammation while simultaneously protecting the stomach from NSAID-induced gastric irritation. This dual-action formulation provides effective pain relief with reduced risk of gastric side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Naproxen Sodium 375 mg
• Esomeprazole Magnesium 20 mg

Indications

Progut-N Tablet is indicated for:

• Osteoarthritis and rheumatoid arthritis
• Ankylosing spondylitis
• Acute musculoskeletal pain
• Back pain and joint pain
• Inflammatory conditions requiring NSAID therapy
• Pain management requiring gastric protection

Mechanism of Action

• Naproxen Sodium inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and thereby decreasing pain, inflammation, and fever.
• Esomeprazole Magnesium reduces gastric acid secretion by irreversibly blocking the proton pump in gastric parietal cells, helping protect the stomach lining from NSAID-induced damage.

Together, they provide effective pain relief with gastrointestinal protection.

Dosage and Administration

• Usually taken once daily or as directed by a physician.
• Swallow whole with water, preferably before meals.
• Do not crush or chew the tablet.
• Dosage depends on condition severity and clinical response.
• Use the lowest effective dose for the shortest duration necessary.

Benefits

• Effective relief from pain and inflammation
• Reduces risk of NSAID-induced gastric ulcers
• Improves joint and muscle mobility
• Convenient single-tablet combination therapy
• Suitable for long-term pain management under supervision

Side Effects

Progut-N Tablet may cause:

• Abdominal discomfort
• Nausea or vomiting
• Headache
• Dizziness
• Increased risk of bleeding (rare)
• Gastric irritation (reduced due to PPI component)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with kidney, liver, or heart disease.
• Long-term NSAID use should be medically supervised.
• May increase risk of cardiovascular events with prolonged use.
• Avoid use in active gastric bleeding or ulcer without medical advice.
• Inform physician about all ongoing medications.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.