Rofurox Injection 750 mg/vial contains Cefuroxime, a second-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to the destruction of susceptible bacteria.

Cefuroxime is effective against both Gram-positive and Gram-negative organisms, making it a broad-spectrum antibiotic suitable for use in hospital and clinical settings. Rofurox Injection is administered parenterally and is indicated for moderate to severe infections where injectable therapy is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum antibacterial activity
  Effective against a wide range of Gram-positive and Gram-negative bacteria.

• Rapid therapeutic action
  Provides effective systemic treatment in moderate to severe infections.

• Suitable for hospital use
  Administered intravenously or intramuscularly under medical supervision.

• Reliable infection control
  Helps reduce complications associated with untreated bacterial infections.

Indications

Rofurox Injection 750 mg/vial is indicated for the treatment of infections caused by susceptible organisms, including:

• Respiratory tract infections (such as pneumonia and bronchitis)

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

• Gynecological infections

• Septicemia

• Intra-abdominal infections

• Surgical prophylaxis to prevent post-operative infections

Therapy should be guided by culture and sensitivity testing whenever possible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Administered by intravenous (IV) or intramuscular (IM) injection.

• Dosage and duration depend on the severity and type of infection.

• The usual adult dose ranges from 750 mg to 1.5 g every 8 hours, as prescribed by a healthcare professional.

• Pediatric dosing is determined based on body weight and clinical condition.

Reconstitution and administration should be performed by qualified healthcare personnel.

Mechanism of Action

Cefuroxime is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disrupts cell wall formation, leading to bacterial cell lysis and death.

Safety Information

Contraindications:

• Known hypersensitivity to cephalosporins or other beta-lactam antibiotics.

Warnings and precautions:

• Use cautiously in patients with a history of penicillin allergy.

• Prolonged use may result in superinfection.

• Dose adjustment may be necessary in patients with renal impairment.

Common side effects may include injection site reactions, diarrhea, nausea, rash, or allergic reactions.

Storage

Store below 25°C in a dry place. Protect from light. Use reconstituted solution as directed and discard unused portion appropriately. Keep out of reach of children.