Salflu Inhalation Capsule 50 mcg+100 mcg is a combination therapy containing Salmeterol 50 mcg, a long-acting beta-2 adrenergic agonist (LABA), and Fluticasone Propionate 100 mcg, an inhaled corticosteroid (ICS). This formulation is designed for the management and long-term control of asthma and chronic obstructive pulmonary disease (COPD), providing both bronchodilation and anti-inflammatory effects.

Salmeterol works to relax the airway muscles, ensuring easier airflow and reducing bronchospasm, while Fluticasone Propionate suppresses airway inflammation, decreases mucus production, and prevents exacerbations. This combination ensures rapid relief from breathing difficulties and sustained control over chronic respiratory symptoms, making it suitable for patients requiring regular maintenance therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each inhalation capsule contains:

• Salmeterol 50 mcg

• Fluticasone Propionate 100 mcg

• Inactive ingredients to stabilize and ensure consistent delivery via a dry powder inhaler (DPI)

Indications

Salflu Inhalation Capsule 50 mcg+100 mcg is indicated for:

• Maintenance treatment of asthma in adults and adolescents

• Prevention of bronchospasm and asthma exacerbations

• Long-term management of COPD to reduce symptoms and improve lung function

• Patients not adequately controlled with ICS alone

• Patients requiring combination therapy for optimal airway management

Mechanism of Action

The combination of Salmeterol and Fluticasone Propionate acts via complementary mechanisms:

1. Salmeterol (Long-acting beta-2 agonist):

   • Stimulates beta-2 adrenergic receptors in airway smooth muscles

   • Causes bronchodilation, improving airflow and reducing symptoms like wheezing, shortness of breath, and chest tightness

   • Provides long-lasting bronchodilation for up to 12 hours, supporting twice-daily dosing

2. Fluticasone Propionate (Inhaled corticosteroid):

   • Suppresses inflammatory mediators in the airways

   • Reduces airway edema, mucus production, and eosinophil activity

   • Prevents chronic airway remodeling and reduces frequency of asthma attacks

Together, they control inflammation and maintain open airways, improving lung function and quality of life in patients with persistent respiratory conditions.

Dosage and Administration

• Adults and adolescents: 1 capsule inhaled twice daily using a dry powder inhaler (DPI)

• Inhale at the same time each day to maintain consistent therapeutic levels

• Do not use as a rescue medication for sudden asthma attacks; a short-acting inhaler should be used in emergencies

• Rinse mouth with water after inhalation to reduce risk of oral thrush and irritation

• Regular monitoring of lung function and symptoms is recommended to adjust therapy if needed

Precautions and Warnings

• Not for acute bronchospasm or asthma attacks

• Use with caution in patients with cardiovascular disease, hypertension, diabetes, or thyroid disorders

• Avoid abrupt discontinuation of Fluticasone Propionate to prevent adrenal insufficiency

• Report any paradoxical bronchospasm, persistent cough, or worsening breathing to a physician immediately

• Children and elderly patients should use under strict medical supervision

Possible Side Effects

Salflu Inhalation Capsule 50 mcg+100 mcg is generally well tolerated. Common side effects include:

• Mild throat irritation or hoarseness

• Oral candidiasis (thrush)

• Headache or dizziness

• Tremors or palpitations (rare, due to Salmeterol)

• Rarely, systemic corticosteroid effects such as suppression of adrenal function

Most side effects are mild and can be minimized with proper inhaler technique and mouth rinsing after use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a cool, dry place below 30°C

• Protect from moisture, heat, and direct sunlight

• Keep out of reach of children

• Do not puncture or swallow the capsules

Conclusion

Salflu Inhalation Capsule 50 mcg+100 mcg (Salmeterol + Fluticasone Propionate) is a highly effective maintenance therapy for asthma and COPD, combining bronchodilation and anti-inflammatory action. Regular use under physician supervision helps control symptoms, prevent exacerbations, and improve respiratory function, offering patients better daily comfort and long-term lung health.