Silinor-M Tablet 50 mg+1000 mg is a combination oral antidiabetic medicine used for the management of type 2 diabetes mellitus. It contains Sitagliptin 50 mg, a DPP-4 inhibitor, and Metformin Hydrochloride 1000 mg, a biguanide class drug. This dual-action formulation helps improve blood sugar control through complementary mechanisms.

Silinor-M is commonly prescribed when diet, exercise, and single-drug therapy are not sufficient to control blood glucose levels effectively.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Sitagliptin 50 mg
• Metformin Hydrochloride 1000 mg

Indications

Silinor-M Tablet 50 mg + 1000 mg is indicated for:

• Type 2 diabetes mellitus
• Inadequate glycemic control with single-agent therapy
• Combination therapy to improve fasting and post-meal blood sugar
• Patients requiring dual mechanism glucose control

How Silinor-M Tablet Works

This combination works through two complementary mechanisms:

• Sitagliptin: Inhibits the DPP-4 enzyme, increasing incretin hormone levels, which enhances insulin secretion and reduces glucagon release in a glucose-dependent manner.
• Metformin: Reduces hepatic glucose production, decreases intestinal glucose absorption, and improves insulin sensitivity.

Together, they provide effective control of both fasting and post-meal blood glucose levels with improved overall glycemic management.

Dosage and Administration

• Take as prescribed by a registered physician.
• Usually taken once or twice daily with meals to reduce gastrointestinal side effects.
• Swallow the tablet whole with water.
• Dosage depends on blood glucose levels, kidney function, and treatment response.

Benefits of Silinor-M Tablet 50 mg + 1000 mg

• Dual-action control of blood sugar levels
• Improves both fasting and post-meal glucose
• Enhances insulin sensitivity and secretion
• More effective than single-drug therapy in many patients
• Helps maintain long-term glycemic control
• Convenient fixed-dose combination therapy

Possible Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Loss of appetite
• Headache
• Upper respiratory tract infection symptoms

Rare but serious effects such as lactic acidosis (from metformin) or pancreatitis should be reported immediately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not recommended for type 1 diabetes or diabetic ketoacidosis
• Use cautiously in patients with kidney or liver impairment
• Regular kidney function monitoring is advised
• May require vitamin B12 monitoring during long-term use
• Avoid excessive alcohol consumption
• Use during pregnancy and breastfeeding only under medical supervision

Storage Instructions

• Store below 30°C in a dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children.