Sutinib Capsule 50 mg contains Sunitinib, a potent targeted therapy used in the treatment of specific types of cancer. Sunitinib is classified as a tyrosine kinase inhibitor (TKI), which works by blocking certain proteins called tyrosine kinases that play a key role in cancer cell growth and angiogenesis (formation of new blood vessels that supply tumors). By inhibiting these pathways, Sutinib helps slow or stop tumor growth and can reduce tumor size.

Sutinib Capsule 50 mg is primarily prescribed for patients with advanced or metastatic cancers where conventional chemotherapy may be less effective. Its oral administration offers convenience while providing systemic anticancer activity.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Indications

Sutinib Capsule 50 mg is indicated for the treatment of:

• Renal Cell Carcinoma (RCC): Advanced or metastatic kidney cancer

• Gastrointestinal Stromal Tumors (GIST): For patients resistant or intolerant to imatinib therapy

• Pancreatic Neuroendocrine Tumors (pNET): Progressive, well-differentiated tumors

• Other solid tumors where Sunitinib is recommended by oncology guidelines

Sutinib is used under the supervision of an oncologist and is part of a comprehensive cancer treatment plan.

Mechanism of Action

Sunitinib is a small-molecule tyrosine kinase inhibitor that targets multiple receptor pathways:

• VEGFR (Vascular Endothelial Growth Factor Receptors): Reduces angiogenesis, limiting the blood supply to tumors

• PDGFR (Platelet-Derived Growth Factor Receptors): Inhibits tumor cell proliferation

• c-KIT and RET: Blocks signaling pathways crucial for tumor growth in GIST and other cancers

By inhibiting these kinases, Sunitinib disrupts tumor blood vessel formation and slows tumor progression while affecting cancer cell survival.

Dosage and Administration

• Recommended Dose: 50 mg once daily, taken orally on a 4-weeks-on, 2-weeks-off schedule, unless otherwise prescribed

• Administration: Swallow the capsule whole with water, preferably at the same time each day

• With or Without Food: Can be taken with or without food

• Consistency: Adherence to the prescribed schedule is critical to maximize efficacy and minimize adverse effects

The dose may be adjusted based on tolerance, response, or side effects under medical supervision.

Benefits of Sutinib Capsule 50 mg

• Targets tumor growth by inhibiting key signaling pathways

• Reduces tumor angiogenesis to limit blood supply to cancer cells

• Provides an oral option for systemic treatment

• Improves progression-free survival in patients with RCC, GIST, and pNET

• Can be combined with other therapies under oncologist guidance for optimal outcomes

Safety Information

Sutinib Capsule may cause side effects, which should be closely monitored:

• Common: Fatigue, diarrhea, nausea, vomiting, loss of appetite, hand-foot syndrome, hypertension

• Serious: Cardiac dysfunction, bleeding, liver toxicity, severe infections, gastrointestinal perforation

Regular monitoring of blood counts, liver and kidney function, and blood pressure is essential during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under oncologist supervision

• Inform the doctor of any heart disease, liver or kidney dysfunction, bleeding disorders, or infections

• Avoid pregnancy; effective contraception is required during treatment and for a period after therapy

• Do not combine with other medications without physician approval due to potential interactions

Why Choose Sutinib Capsule 50 mg

Sutinib Capsule 50 mg provides targeted cancer therapy by inhibiting multiple tyrosine kinase pathways. It is effective in slowing tumor growth, controlling progression in advanced cancers, and offering a convenient oral treatment option under professional medical supervision. With proper monitoring, it can significantly improve patient outcomes in renal cell carcinoma, GIST, and pancreatic neuroendocrine tumors.