Symbion Inhaler (400 mcg+12 mcg)/puff is a high-strength combination inhalation therapy containing Budesonide and Formoterol Fumarate. It is specially formulated for the maintenance treatment of moderate to severe asthma and chronic obstructive pulmonary disease (COPD) in patients who require a higher dose of inhaled corticosteroid along with long-acting bronchodilation.

Asthma and COPD are chronic inflammatory airway disorders characterized by airflow limitation, bronchial inflammation, and increased mucus production. Without proper long-term management, these conditions may lead to frequent exacerbations, reduced lung function, and impaired quality of life. Symbion Inhaler provides dual therapeutic action by combining an anti-inflammatory agent with a long-acting bronchodilator, ensuring comprehensive respiratory control.

This inhaler delivers a precise and consistent dose with each puff, allowing direct deposition of medication into the lungs for optimal clinical effectiveness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Symbion Inhaler (400 mcg+12 mcg)/puff is indicated for:

• Maintenance treatment of moderate to severe bronchial asthma

• Patients not adequately controlled on inhaled corticosteroids alone

• Maintenance therapy of chronic obstructive pulmonary disease (COPD)

• Reduction of asthma and COPD exacerbations

This inhaler is not intended for immediate relief of acute bronchospasm. A short-acting rescue inhaler should be used for sudden breathing difficulties.

Therapeutic Class

Combined inhaled corticosteroid (ICS) and long-acting beta2-agonist (LABA)

Pharmacology

Budesonide is a potent inhaled corticosteroid that reduces airway inflammation by inhibiting inflammatory mediators and immune cell activity in the bronchial mucosa. It decreases airway swelling, mucus secretion, and hyperresponsiveness, thereby improving long-term asthma and COPD control.

Formoterol Fumarate is a selective long-acting beta2-adrenergic agonist. It relaxes bronchial smooth muscle by stimulating beta2 receptors, resulting in prolonged bronchodilation. Formoterol has a rapid onset of action and provides sustained airway relaxation for up to 12 hours.

The combination of these two agents ensures both control of inflammation and sustained bronchodilation, helping patients maintain stable lung function and improved breathing comfort.

Dosage and Administration

The dosage should be individualized according to disease severity and physician recommendation. Generally, one puff is taken once or twice daily as prescribed.

Instructions for proper use:

• Shake the inhaler well before each use.

• Inhale deeply and steadily while pressing the canister.

• Hold the breath for several seconds after inhalation.

• Rinse the mouth with water after each dose to minimize the risk of oral candidiasis.

Regular and consistent use is essential for optimal therapeutic benefit.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Not suitable for treating acute asthma attacks.

• Use cautiously in patients with cardiovascular disorders, diabetes, hyperthyroidism, or seizure disorders.

• Avoid abrupt discontinuation without medical advice.

Side Effects

Possible side effects include:

• Oral thrush

• Hoarseness or throat irritation

• Headache

• Tremor

• Palpitations

Most adverse effects are mild and can be reduced with correct inhalation technique and proper mouth rinsing.

Use in Pregnancy and Lactation

Use during pregnancy and breastfeeding should be considered only if clearly necessary and under medical supervision.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Symbion Inhaler (400 mcg+12 mcg)/puff offers effective, high-strength maintenance therapy for patients requiring enhanced asthma and COPD control, supporting improved respiratory health and long-term disease stability.