Tapina Cream 1% contains Tapinarof, a novel topical therapeutic agent used for the treatment of chronic inflammatory skin conditions, most notably plaque psoriasis. Tapinarof is an aryl hydrocarbon receptor (AhR) agonist that works by modulating the skin’s immune response and restoring skin barrier function. Its unique mechanism helps reduce inflammation, decrease abnormal skin cell proliferation, and improve the overall health and appearance of affected skin.

Plaque psoriasis is a chronic autoimmune skin disorder characterized by thickened, red, and scaly plaques that cause itching, discomfort, and sometimes pain. Tapina Cream 1% provides a non-steroidal option for patients seeking effective local therapy without the risks associated with long-term corticosteroid use. By targeting the underlying inflammatory pathways, Tapina promotes sustained improvement in skin lesions and supports healthier skin.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tapina Cream 1% is indicated for:

• Treatment of plaque psoriasis in adults

• Chronic inflammatory skin conditions characterized by erythema, scaling, and plaque formation

• Patients seeking a topical non-steroidal therapy for moderate-to-severe skin lesions

Therapeutic Class

Topical non-steroidal immunomodulator

Pharmacology

Tapinarof selectively activates the aryl hydrocarbon receptor (AhR) in skin cells. Activation of AhR regulates genes involved in skin homeostasis, keratinocyte differentiation, and inflammation. Specifically, Tapinarof:

• Reduces the production of inflammatory cytokines in the skin

• Normalizes keratinocyte proliferation to prevent thickening of the skin

• Enhances skin barrier function, improving hydration and reducing irritation

Unlike corticosteroids or vitamin D analogs, Tapinarof does not cause skin thinning or long-term hormonal effects, making it suitable for chronic use in adults. Its targeted action ensures localized therapeutic benefits with minimal systemic absorption.

Dosage and Administration

Tapina Cream 1% should be applied once or twice daily as prescribed by a healthcare professional:

• Apply a thin layer of cream to the affected areas of the skin

• Gently rub the cream until fully absorbed

• Wash hands thoroughly after application

• Avoid applying on mucous membranes, open wounds, or infected skin

Consistency in application is crucial for achieving optimal results. Improvement may be observed within several weeks, with continued use providing sustained control of skin lesions.

Precautions

• Avoid contact with eyes and mucous membranes

• Not recommended for use in children or adolescents under the guidance of a physician

• Discontinue use if signs of skin infection, rash worsening, or hypersensitivity occur

• Use cautiously in patients with a history of allergic reactions to topical medications

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Tapina Cream 1% is generally well tolerated. Common side effects may include:

• Mild skin irritation or redness at the application site

• Itching or burning sensation

• Dryness or peeling of the treated skin

• Rare allergic reactions

Most side effects are mild and temporary, resolving with continued use or short-term discontinuation.

Storage

Store at room temperature below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Tapina Cream 1% (Tapinarof) offers an effective, non-steroidal treatment option for plaque psoriasis and other chronic inflammatory skin conditions, promoting healthier skin, reducing lesions, and improving patient comfort and quality of life.