Tricalm Tablet 2 mg contains Trihexyphenidyl Hydrochloride, an anticholinergic agent used to manage Parkinson’s disease and drug-induced extrapyramidal symptoms (EPS). Trihexyphenidyl works by restoring the balance between dopamine and acetylcholine in the brain, helping to reduce muscle stiffness, tremors, and involuntary movements.

Tricalm provides relief from motor symptoms, improving mobility, coordination, and daily functioning for patients with Parkinsonism or EPS caused by antipsychotic medications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tricalm Tablet is indicated for:

• Parkinson’s disease to control tremors, rigidity, and bradykinesia
• Drug-induced extrapyramidal symptoms such as dystonia, akathisia, or tremors
• Adjunct therapy for patients with Parkinsonism who do not achieve adequate symptom control with other medications
• Improvement of motor function and daily activity performance

Mechanism of Action

Trihexyphenidyl acts as an anticholinergic agent:

• Blocks muscarinic acetylcholine receptors in the central nervous system
• Restores the dopamine-acetylcholine balance in the basal ganglia
• Reduces tremors, muscle stiffness, and involuntary movements
• Enhances motor control and coordination

By modulating neurotransmitter activity, Tricalm alleviates key motor symptoms of Parkinsonism and EPS.

Dosage and Administration

• Initial dose: 1–2 mg orally, 2–3 times daily; may be gradually increased based on response and tolerability
• Take tablets with or without food
• Do not exceed the prescribed dose
• For elderly patients, start with the lowest effective dose to minimize side effects
• Dose adjustment may be needed in renal or hepatic impairment

Benefits

• Reduces tremors, rigidity, and involuntary movements
• Improves coordination and balance
• Enhances mobility and daily functioning
• Provides effective management of drug-induced movement disorders
• Simple oral therapy for consistent symptom control

Side Effects

Common side effects may include:

• Dry mouth
• Blurred vision
• Constipation
• Drowsiness or dizziness
• Nausea

Serious but rare side effects:

• Confusion or hallucinations, especially in elderly patients
• Urinary retention or difficulty urinating
• Rapid heartbeat (tachycardia)
• Severe allergic reactions

Contact a physician immediately if severe cognitive changes, urinary problems, or cardiovascular symptoms occur.

Precautions and Warnings

• Use with caution in elderly patients due to increased risk of confusion and hallucinations
• Avoid in patients with glaucoma, severe constipation, urinary obstruction, or cardiac arrhythmias
• May impair the ability to drive or operate machinery
• Pregnancy and breastfeeding: use only under medical supervision
• Monitor closely for cognitive changes or worsening Parkinsonian symptoms

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Trihexyphenidyl may interact with:

• Other anticholinergic drugs (additive effects)
• CNS depressants (increased sedation)
• Antihypertensives (may alter blood pressure)
• Antipsychotic medications (dose adjustments may be required)

Inform your healthcare provider of all medications and supplements before starting therapy.

Storage

• Store below 25°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after the expiration date.