Tritide Inhalation Capsule is a triple-combination therapy designed for the management of chronic obstructive pulmonary disease (COPD) and severe asthma. It contains three active ingredients:

• Vilanterol Trifenatate (25 mcg): A long-acting beta-2 adrenergic agonist (LABA) that relaxes airway muscles to improve airflow.

• Fluticasone Furoate (100 mcg): An inhaled corticosteroid (ICS) that reduces airway inflammation and swelling.

• Umeclidinium Bromide (62.5 mcg): A long-acting muscarinic antagonist (LAMA) that helps prevent bronchoconstriction by relaxing airway smooth muscles.

This combination provides 24-hour symptom relief, improves lung function, and reduces the frequency of COPD exacerbations and asthma attacks. Tritide is intended for maintenance therapy and is not a rescue medication for sudden breathing difficulties.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Vilanterol Trifenatate: 25 mcg

• Fluticasone Furoate: 100 mcg

• Umeclidinium Bromide: 62.5 mcg

• Dosage Form: Inhalation capsule

• Pharmacological Class: LABA + ICS + LAMA (Bronchodilator + Anti-inflammatory combination)

Mechanism of Action

Vilanterol Trifenatate (LABA): Stimulates beta-2 adrenergic receptors in the lungs, causing relaxation of airway smooth muscles, leading to bronchodilation and improved airflow.

Fluticasone Furoate (ICS): Reduces airway inflammation by suppressing immune responses, helping decrease swelling, mucus production, and hyperreactivity of the airways.

Umeclidinium Bromide (LAMA): Blocks muscarinic receptors in the airways, preventing bronchoconstriction and keeping airways open for longer durations.

The combination of these three agents offers a synergistic effect, targeting both inflammation and airway constriction for better control of respiratory symptoms.

Indications

Tritide Inhalation Capsule is indicated for:

• Maintenance treatment of chronic obstructive pulmonary disease (COPD)

• Severe asthma not adequately controlled with a LABA/ICS combination

• Reducing exacerbations and hospitalization risk in COPD patients

• Improving lung function, exercise tolerance, and quality of life in chronic respiratory conditions

Dosage and Administration

• Each inhalation capsule is administered via a dry powder inhaler (DPI).

• The typical dosage is one capsule once daily, or as prescribed by a physician.

• Do not swallow the capsule; it is for inhalation only.

• Rinse the mouth with water after inhalation to reduce the risk of oral thrush caused by corticosteroids.

• Tritide is intended for regular daily use; it is not suitable for immediate relief of sudden symptoms.

Benefits

• Provides 24-hour bronchodilation and anti-inflammatory action

• Reduces the frequency of COPD and asthma exacerbations

• Improves lung function and airflow

• Enhances exercise tolerance and daily activity in patients with chronic respiratory conditions

• Combines three mechanisms of action for comprehensive symptom control

Possible Side Effects

Common side effects may include:

• Headache

• Throat irritation or hoarseness

• Cough

• Oral fungal infection (thrush)

• Tremor or palpitations

Serious but rare side effects:

• Severe allergic reactions

• Paradoxical bronchospasm

• Increased heart rate or blood pressure

• Eye problems (glaucoma or cataracts with long-term steroid use)

Patients should consult their doctor if side effects are severe or persistent.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use under medical supervision; not for acute symptom relief.

• Avoid sudden discontinuation; follow the prescribed regimen.

• Rinse mouth after each use to prevent fungal infections.

• Caution in patients with heart disease, hypertension, or glaucoma.

• Inform your doctor about all current medications to prevent interactions.

Storage

• Store capsules in a cool, dry place below 30°C.

• Keep in the original packaging until use to protect from moisture.

• Keep out of reach of children.