Twicef Capsule 500 mg contains Cefadroxil Monohydrate, a first-generation cephalosporin antibiotic used for the treatment of a variety of bacterial infections. Cefadroxil is well known for its effectiveness against susceptible Gram-positive and certain Gram-negative bacteria. It works by killing bacteria and preventing the spread of infection in the body.

Twicef Capsule is commonly prescribed for mild to moderate infections affecting the respiratory tract, skin, urinary tract, and other body systems. Due to its favorable safety profile and convenient dosing schedule, it is widely used in outpatient settings.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Cefadroxil Monohydrate equivalent to Cefadroxil 500 mg

It may also include standard pharmaceutical excipients suitable for oral capsule formulation.

Mechanism of Action

Cefadroxil is a beta-lactam antibiotic belonging to the cephalosporin class. It works by:

• Inhibiting bacterial cell wall synthesis

• Binding to specific penicillin-binding proteins (PBPs)

• Preventing the formation of peptidoglycan cross-links essential for bacterial cell wall strength

• Causing cell wall rupture and bacterial death

Cefadroxil is bactericidal in nature, meaning it actively kills bacteria rather than merely inhibiting their growth.

Indications

Twicef Capsule 500 mg is indicated for the treatment of infections caused by susceptible organisms, including:

• Upper respiratory tract infections (e.g., tonsillitis, pharyngitis)

• Lower respiratory tract infections (e.g., bronchitis)

• Skin and soft tissue infections

• Urinary tract infections (UTIs)

• Bone and joint infections

• Impetigo and other bacterial skin conditions

It may also be prescribed in certain cases for prophylactic use as directed by a healthcare professional.

Dosage and Administration

• Adults: Typically 500 mg to 1 g daily, given as a single dose or divided into two doses, depending on infection severity

• Children: Dose adjusted according to body weight and medical advice

• Capsules should be swallowed whole with water

• Can be taken with or without food

The duration of therapy usually ranges from 5 to 14 days, depending on the infection type and clinical response. It is important to complete the full prescribed course to prevent bacterial resistance.

Precautions and Warnings

• Contraindicated in patients with known hypersensitivity to cephalosporins

• Use caution in patients with a history of penicillin allergy

• Dosage adjustment may be required in renal impairment

• Prolonged use may lead to superinfection with non-susceptible organisms

• Use during pregnancy and breastfeeding only under medical supervision

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Twicef Capsule is generally well tolerated. Possible side effects include:

• Nausea or vomiting

• Diarrhea

• Abdominal discomfort

• Skin rash or itching

• Rare: allergic reactions, including anaphylaxis

If severe diarrhea or allergic reactions occur, medical attention should be sought immediately.

Storage

Store below 30°C in a cool, dry place. Protect from moisture and direct sunlight. Keep out of reach of children.

Conclusion

Twicef Capsule 500 mg (Cefadroxil Monohydrate) is a reliable and effective oral antibiotic for the treatment of various bacterial infections. Its bactericidal action, convenient dosing, and established safety profile make it a trusted option for managing common community-acquired infections. Proper use under medical supervision ensures optimal results and helps prevent antibiotic resistance.