Viera Tablet 200 mg contains Voriconazole, a broad-spectrum antifungal medication used to treat serious and life-threatening fungal infections. It belongs to the triazole class of antifungals and is particularly effective against invasive Aspergillus and Candida species.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Viera Tablet is indicated for:

• Invasive aspergillosis
• Candidemia (Candida infections in the bloodstream)
• Esophageal candidiasis
• Serious fungal infections resistant to other antifungal agents
• Fungal infections in immunocompromised patients (e.g., cancer, transplant recipients)

Mechanism of Action

Voriconazole works by inhibiting fungal cytochrome P450–dependent enzyme (14-alpha-sterol demethylase), which is essential for ergosterol synthesis. This leads to:

• Disruption of fungal cell membrane formation
• Increased membrane permeability
• Inhibition of fungal growth and replication
• Eventual fungal cell death

Dosage and Administration

• Taken orally as prescribed by a physician
• Usually administered every 12 hours after an initial loading dose
• Should be taken at least 1 hour before or 1 hour after meals
• Tablets should be swallowed whole with water
• Dosage may vary depending on infection severity and patient condition

Benefits

• Effective against a wide range of serious fungal infections
• First-line therapy for invasive aspergillosis
• Suitable for immunocompromised patients
• Available in oral form for continued therapy after IV treatment
• Helps improve survival in severe fungal infections

Side Effects

Common side effects may include:

• Visual disturbances (blurred vision, light sensitivity)
• Nausea and vomiting
• Headache
• Rash
• Elevated liver enzymes

Serious side effects:

• Liver toxicity
• Severe skin reactions (including photosensitivity)
• Cardiac rhythm disturbances
• Hallucinations or neurological effects

Precautions and Warnings

• Regular monitoring of liver function is essential
• Avoid excessive sunlight exposure (risk of photosensitivity)
• Use cautiously in patients with liver disease
• Not recommended during pregnancy unless clearly necessary
• Dose adjustments may be required in renal or hepatic impairment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Viera Tablet may interact with:

• Rifampicin and other enzyme inducers (reduce effectiveness)
• Certain anticonvulsants (e.g., phenytoin)
• Warfarin (increased bleeding risk)
• Cyclosporine and tacrolimus (increased drug levels)
• Other drugs metabolized by CYP450 enzymes

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.