Vonomax Trio Tablet is a fixed-dose combination therapy containing Vonoprazan, Amoxicillin, and Clarithromycin. It is specifically formulated as a triple therapy regimen used for the effective eradication of Helicobacter pylori (H. pylori) infection, a common cause of gastritis, peptic ulcer disease, and increased risk of gastric complications if left untreated.

This combination works by reducing stomach acid secretion and directly targeting the bacterial infection, ensuring higher eradication rates and improved healing of gastric and duodenal ulcers.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition and Mechanism of Action

• Vonoprazan 20 mg: A potassium-competitive acid blocker (P-CAB) that suppresses gastric acid secretion rapidly and more consistently than conventional proton pump inhibitors. It creates an optimal environment for antibiotics to act effectively.
• Amoxicillin 1000 mg: A broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to the destruction of H. pylori bacteria.
• Clarithromycin 500 mg: A macrolide antibiotic that inhibits bacterial protein synthesis, enhancing eradication of resistant or persistent H. pylori strains.

Therapeutic Indications

Vonomax Trio Tablet is indicated for:

• Eradication of Helicobacter pylori infection
• Treatment of peptic ulcer disease associated with H. pylori
• Prevention of ulcer recurrence after initial healing
• Management of gastritis caused by bacterial infection

Dosage and Administration

• The tablet is generally taken as part of a prescribed short-term therapy regimen.
• It is usually administered twice daily for a specific duration as directed by a physician.
• Should be taken after meals with a full glass of water.
• Do not skip doses to ensure complete eradication of infection.

Dosage should always be determined by a qualified healthcare professional based on patient condition and medical history.

Contraindications

• Known allergy to Vonoprazan, Amoxicillin, Clarithromycin, or other macrolide/penicillin antibiotics
• History of severe liver impairment
• Concurrent use with medications that may cause serious drug interactions (as advised by physician)

Possible Side Effects

Some patients may experience:

• Nausea or vomiting
• Diarrhea or abdominal discomfort
• Headache
• Taste disturbances
• Skin rash or allergic reactions (rare but serious)

Seek immediate medical attention if severe allergic reactions or persistent side effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use with caution in patients with liver or kidney disorders
• Inform the physician about all ongoing medications
• Avoid alcohol during treatment
• Complete the full course even if symptoms improve early

Storage Instructions

• Store in a cool, dry place away from direct sunlight
• Keep out of reach of children
• Do not use expired medicine.