Wilpen Capsule 250 mg contains Penicillamine, a chelating agent and disease-modifying medicine used mainly in Wilson’s disease, cystinuria, and severe rheumatoid arthritis. It helps remove excess copper and other heavy metals from the body through urine, making it highly effective in conditions where toxic metal accumulation causes organ damage.

In Wilson’s disease, a genetic disorder, copper accumulates in vital organs such as the liver, brain, and eyes. Penicillamine binds with excess copper and promotes its excretion, helping prevent liver failure, neurological damage, and other complications. In cystinuria, it reduces cystine levels in urine and helps prevent kidney stone formation. In rheumatoid arthritis, it is used as a second-line disease-modifying antirheumatic drug (DMARD) when first-line therapies are insufficient.

Wilpen Capsule 250 mg should be used under strict medical supervision due to its potent action and potential for serious side effects. Long-term treatment requires regular monitoring of blood counts, kidney function, and urine protein levels to ensure safe and effective therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Penicillamine BP 250 mg

Indications

Wilpen Capsule is indicated for:

• Wilson’s disease (hepatolenticular degeneration)
• Cystinuria (prevention of cystine kidney stones)
• Severe rheumatoid arthritis (second-line therapy)
• Heavy metal toxicity (especially copper overload)

How It Works

Penicillamine acts as a chelating agent by binding to copper and other heavy metals in the bloodstream. The resulting complexes are eliminated through urine, reducing toxic accumulation and preventing damage to organs such as the liver and brain.

Dosage and Administration

The dosage must be strictly determined by a registered physician.

• Dose varies depending on condition, severity, and patient response
• Usually taken on an empty stomach for better absorption
• Long-term therapy requires careful dose adjustment and regular monitoring

Benefits of Wilpen Capsule

• Helps eliminate excess copper from the body
• Prevents progression of Wilson’s disease
• Reduces risk of kidney stone formation in cystinuria
• Acts as a second-line DMARD in rheumatoid arthritis
• Supports long-term control of metal-related disorders

Precautions

Use cautiously in:

• Kidney impairment
• Bone marrow suppression
• History of severe allergic reactions to penicillamine
• Pregnancy and breastfeeding (only if clearly necessary)

Regular monitoring of blood counts, kidney function, and urine protein is essential during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Loss of appetite
• Skin rash
• Altered taste sensation
• Proteinuria
• Joint pain or fatigue

Serious side effects may include:

• Bone marrow suppression
• Severe allergic reactions
• Kidney problems

Seek immediate medical attention if fever, sore throat, unusual bleeding, or severe weakness occurs.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.