Xadu Tablet 70 mg contains Roxadustat, an advanced oral medication used for the treatment of anemia associated with chronic kidney disease (CKD). Roxadustat belongs to the therapeutic class of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) and is designed to correct anemia by activating the body’s natural response to low oxygen levels. It provides an effective and convenient alternative to injectable erythropoiesis-stimulating agents, particularly for patients requiring long-term therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Roxadustat 70 mg

• Dosage form: Tablet

• Route of administration: Oral

Mechanism of Action

Roxadustat works by inhibiting prolyl hydroxylase enzymes that normally degrade hypoxia-inducible factors (HIFs). Stabilization of HIFs triggers the transcription of genes involved in erythropoiesis, leading to increased physiological production of endogenous erythropoietin in the kidneys and liver. In addition, Roxadustat reduces hepcidin levels, improves intestinal iron absorption, enhances mobilization of stored iron, and promotes efficient hemoglobin synthesis. This dual effect addresses both erythropoietin deficiency and impaired iron metabolism commonly seen in CKD-related anemia.

Indications

Xadu Tablet 70 mg is indicated for:

• Treatment of anemia in patients with chronic kidney disease

• Management of anemia in both dialysis-dependent and non-dialysis CKD patients, as prescribed

• Correction and maintenance of hemoglobin levels

• Reduction of anemia-related symptoms such as fatigue, weakness, and decreased exercise capacity

Dosage and Administration

The dosage of Xadu Tablet 70 mg should be individualized by a healthcare professional based on patient body weight, baseline hemoglobin concentration, and clinical response. It is taken orally at scheduled intervals. The tablet should be swallowed whole with water and may be taken with or without food. Regular monitoring of hemoglobin levels, iron parameters, and overall clinical status is essential throughout treatment.

Benefits and Key Features

• Oral treatment option for CKD-related anemia

• Supports natural erythropoietin production

• Improves iron availability and utilization

• Helps maintain stable hemoglobin levels

• Reduces the need for injectable anemia therapies

• Enhances patient convenience and treatment adherence

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

Xadu Tablet 70 mg is generally well tolerated when used under medical supervision. Commonly reported side effects may include headache, nausea, diarrhea, hypertension, hyperkalemia, or upper respiratory tract infections. Careful monitoring is required to prevent excessive increases in hemoglobin levels. Caution is advised in patients with cardiovascular disease, liver impairment, or a history of thromboembolic disorders. Use during pregnancy and breastfeeding should be based strictly on medical advice.

Patients should inform their physician about all current medications and existing medical conditions before starting therapy.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Xadu Tablet 70 mg from SK Pharma offers a balanced and patient-friendly solution for the management of anemia in chronic kidney disease, helping restore hemoglobin levels and improve overall quality of life through advanced oral therapy.