Xidolac Injection 30 mg/ml contains Ketorolac Tromethamine, a powerful non-steroidal anti-inflammatory drug (NSAID) used for the short-term management of moderate to severe acute pain. This higher-strength injectable formulation is designed for rapid and effective pain relief in hospital and emergency settings, particularly when oral analgesics are not suitable. Ketorolac provides strong analgesic efficacy comparable to opioid medications, without the risk of dependence or respiratory depression.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Indications

Xidolac Injection 30 mg/ml is indicated for short-term treatment of moderate to severe pain, including:

• Postoperative pain management

• Acute pain following trauma or injury

• Renal colic

• Severe musculoskeletal pain

• Acute gynecological or dental pain, as prescribed by a physician

This injection is intended for short-duration use only and may be followed by oral pain management once the patient’s condition stabilizes.

Mechanism of Action

Ketorolac Tromethamine acts by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are essential for the synthesis of prostaglandins. Prostaglandins are chemical mediators responsible for pain, inflammation, and swelling. By reducing prostaglandin production, Xidolac Injection 30 mg/ml effectively relieves pain and inflammation, providing rapid and sustained analgesic action.

Dosage and Administration

Xidolac Injection 30 mg/ml must be administered by trained healthcare professionals only.

• It can be given via intramuscular (IM) or intravenous (IV) injection, depending on clinical needs.

• The dosage is individualized based on the severity of pain, patient age, body weight, and renal function.

• Elderly patients and those with renal impairment generally require lower doses.

• The total combined duration of ketorolac therapy, including injectable and oral forms, should not exceed 5 days.

Precautions and Warnings

• Xidolac Injection should be used with caution in patients with kidney disease, bleeding disorders, peptic ulcer disease, or cardiovascular conditions.

• It is contraindicated in patients with active gastrointestinal bleeding, severe renal impairment, or known hypersensitivity to ketorolac or other NSAIDs.

• Concurrent use with other NSAIDs, corticosteroids, or anticoagulants increases the risk of bleeding and should be avoided unless strictly necessary.

• Use during pregnancy, particularly in the third trimester, and during breastfeeding is generally not recommended unless clearly advised by a physician.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Like other NSAIDs, Xidolac Injection 30 mg/ml may cause side effects, especially at higher doses. Common side effects include:

• Nausea and vomiting

• Dizziness or headache

• Injection site pain or inflammation

• Gastrointestinal discomfort

Serious adverse effects such as gastrointestinal bleeding, kidney impairment, or severe allergic reactions are uncommon but require immediate medical attention.

Storage

Store Xidolac Injection 30 mg/ml in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.

Conclusion

Xidolac Injection 30 mg/ml is a strong and fast-acting analgesic option for the short-term management of moderate to severe acute pain. When used appropriately under medical supervision, it provides effective pain relief while minimizing reliance on opioid analgesics.