Zerotil Injection 750 mg/Vial contains Cefuroxime Axetil, a second-generation cephalosporin antibiotic used for the treatment of moderate to severe bacterial infections. It is administered parenterally in hospital settings when rapid and reliable antibiotic action is required or when oral therapy is not suitable. Cefuroxime works by killing bacteria through inhibition of cell wall synthesis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Zerotil Injection is indicated for the treatment of:

• Lower respiratory tract infections (pneumonia, bronchitis)
• Severe ENT infections (sinusitis, otitis media)
• Urinary tract infections, including complicated cases
• Skin and soft tissue infections
• Bone and joint infections (as prescribed)
• Septicemia and other serious systemic infections

Mechanism of Action

Cefuroxime is a bactericidal cephalosporin antibiotic. After administration, it inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disrupts cell wall formation, leading to bacterial cell lysis and death. It is effective against a wide range of Gram-positive and Gram-negative organisms.

Dosage and Administration

• Administered intravenously (IV) or intramuscularly (IM) by healthcare professionals only
• Dosage depends on type and severity of infection and patient condition
• Reconstitute vial as per manufacturer instructions before use
• Given at regular intervals as prescribed by the physician
• Dose adjustment may be required in renal impairment
• Treatment duration is based on clinical response

Benefits

• Rapid and effective treatment for serious bacterial infections
• Broad-spectrum activity against many pathogens
• Suitable for hospital and emergency use
• Helps prevent complications of untreated infections
• Reliable parenteral antibiotic therapy

Side Effects

Common side effects may include:

• Pain or swelling at injection site
• Nausea or vomiting
• Diarrhea
• Headache
• Rash

Serious side effects (rare):

• Allergic reactions (anaphylaxis, swelling, breathing difficulty)
• Severe diarrhea (Clostridium difficile infection)
• Liver enzyme elevation
• Blood disorders such as leukopenia or thrombocytopenia

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For intravenous or intramuscular use only under medical supervision
• Not effective against viral infections
• Use cautiously in patients with penicillin or cephalosporin allergy
• Dose adjustment required in renal impairment
• Complete full course to prevent antibiotic resistance
• Inform physician about other medications being used

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Use freshly prepared solution as directed
• Keep out of reach of children.