Zoclast Injection 4 mg/5 ml contains Zoledronic Acid, a potent bisphosphonate used for the treatment of hypercalcemia of malignancy and bone-related disorders associated with cancer. It helps reduce elevated calcium levels in the blood and strengthens bone by inhibiting excessive bone resorption.

Zoledronic Acid works by blocking the activity of osteoclasts, the cells responsible for bone breakdown. In conditions like malignancy-associated hypercalcemia, excessive bone resorption releases calcium into the bloodstream. By inhibiting this process, Zoclast Injection helps normalize serum calcium levels and provides long-lasting control.

This medicine is administered intravenously in a hospital setting under strict medical supervision. It is considered highly effective for rapid and sustained reduction of high calcium levels and is also used in other bone metastasis-related conditions as advised by an oncologist.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Zoledronic Acid BP 4 mg/5 ml

Indications

Zoclast Injection is indicated for:

• Hypercalcemia of malignancy
• Bone metastases in cancer patients
• Multiple myeloma-related bone disease
• Prevention of skeletal-related events in cancer
• Bone resorption disorders associated with malignancy

How It Works

Zoledronic Acid binds to bone mineral and inhibits osteoclast-mediated bone resorption. This reduces calcium release from bones into the bloodstream, helping restore normal calcium levels and reducing bone complications.

Dosage and Administration

The dosage must be administered by a qualified healthcare professional.

• Given as a slow intravenous infusion
• Dose depends on serum calcium levels, renal function, and clinical condition
• Adequate hydration is recommended before administration
• Kidney function must be monitored before and after treatment

Benefits of Zoclast Injection

• Rapid reduction of high blood calcium levels
• Long-lasting control of hypercalcemia
• Helps prevent bone complications in cancer
• Strengthens bone and reduces fractures
• Useful in malignancy-related bone disease

Precautions

Use cautiously in:

• Kidney impairment
• Dehydration
• Hypocalcemia (must be corrected before treatment)
• Elderly patients
• Pregnancy and breastfeeding (contraindicated unless essential)

Renal function and serum calcium should be closely monitored during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Fever and flu-like symptoms
• Bone or joint pain
• Nausea
• Fatigue
• Headache
• Injection-related reactions

Serious side effects may include kidney dysfunction, severe hypocalcemia, and osteonecrosis of the jaw.

Storage

• Store below 25–30°C
• Protect from light
• Do not freeze
• Keep out of reach of children.