Zodef Tablet 18 mg contains Deflazacort, a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. It is prescribed for the treatment of a variety of inflammatory, allergic, and autoimmune conditions, including rheumatic disorders, asthma, and muscular dystrophies.

Deflazacort is known for its effective inflammation control with relatively fewer corticosteroid-related side effects, such as bone loss or weight gain, making it suitable for both short-term and long-term therapy. Zodef Tablet 18 mg offers a moderate dosage strength, providing flexibility in dosing for patients requiring adjustment based on condition severity.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Anti-Inflammatory Action: Reduces swelling, pain, and redness associated with inflammation.
• Immunosuppressive Effect: Helps control autoimmune disorders by modulating the immune system.
• Supports Muscle Function: Beneficial in muscular dystrophy to improve strength and mobility.
• Convenient Oral Form: Easy-to-administer tablet for daily use.
• Moderate Dosage Strength: Suitable for patients requiring mid-range corticosteroid therapy.

Mechanism of Action

Deflazacort works by suppressing inflammatory and immune responses. It inhibits the production of inflammatory mediators and cytokines, reducing tissue damage, swelling, and pain. Additionally, it modulates gene expression involved in immune regulation, offering broad anti-inflammatory and immunosuppressive effects.

Indications

Zodef Tablet 18 mg is indicated for:

• Rheumatic and musculoskeletal disorders (e.g., rheumatoid arthritis, lupus)
• Allergic conditions (e.g., asthma, eczema, allergic rhinitis)
• Autoimmune diseases requiring immunosuppressive therapy
• Muscular dystrophies, including Duchenne Muscular Dystrophy
• Other inflammatory and immune-mediated conditions as prescribed by a physician

Dosage and Administration

• Dosage is individualized based on patient condition, age, and response to therapy.
• Typically administered once daily in the morning to align with natural cortisol rhythms.
• Take with water, preferably after meals to reduce gastrointestinal discomfort.
• Do not discontinue therapy abruptly; tapering is required for long-term use.
• Follow the doctor’s instructions carefully for safe and effective therapy.

Precautions

• Use cautiously in patients with diabetes, hypertension, infections, or gastrointestinal issues.
• Avoid live vaccines during corticosteroid therapy.
• Long-term use may require monitoring of bone density, blood sugar, and eye health.
• Pregnant or breastfeeding women should use only under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects:

• Increased appetite and weight gain
• Mood changes, anxiety, or insomnia
• Mild gastrointestinal discomfort
• Fluid retention

Rare but serious side effects:

• Osteoporosis with prolonged use
• Elevated blood sugar
• Increased susceptibility to infections
• Adrenal suppression

Seek immediate medical attention if severe side effects or unusual symptoms occur.

Storage

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.