A-Cal Tablet 500 mg contains Calcium Carbonate, a widely used calcium supplement that helps maintain healthy bones and teeth. Calcium is an essential mineral required for multiple physiological functions, including bone mineralization, muscle contraction, nerve transmission, and normal cardiac function. A-Cal Tablet 500 mg is indicated for the prevention and treatment of calcium deficiency and related bone disorders.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

A-Cal Tablet 500 mg is used in the management and prevention of conditions associated with low calcium levels, such as:

• Calcium deficiency due to inadequate dietary intake

• Osteoporosis (including postmenopausal and senile osteoporosis)

• Osteomalacia and rickets

• Hypocalcemia

• Increased calcium requirements during pregnancy and lactation

• Calcium supplementation in elderly patients

• As an adjunct therapy during fracture healing

Adequate calcium intake is crucial for individuals with increased needs or reduced absorption to maintain skeletal strength and overall health.

Therapeutic Class

Mineral supplements

Pharmacology

Calcium plays a vital role in bone formation and maintenance. About 99% of the body’s calcium is stored in bones and teeth, while the remaining 1% is involved in critical metabolic processes. Calcium Carbonate provides a concentrated source of elemental calcium and is best absorbed when taken with food, as gastric acid enhances its solubility.

Calcium is essential for neuromuscular activity, blood coagulation, enzymatic reactions, and cardiac muscle contraction. Deficiency can lead to bone demineralization, muscle cramps, paresthesia, and an increased risk of fractures. Calcium absorbed from the gastrointestinal tract is regulated by vitamin D, parathyroid hormone, and calcitonin to maintain calcium homeostasis.

Mode of Action

Calcium Carbonate dissociates in the stomach to release calcium ions, which are absorbed in the small intestine. These ions contribute to bone mineral density and support normal muscle and nerve function. Supplementation with A-Cal Tablet 500 mg helps restore and maintain normal calcium levels, thereby preventing bone loss and reducing the risk of skeletal disorders.

Dosage and Administration

The dosage depends on age, dietary intake, and clinical condition:

• Adults: 500–1000 mg of elemental calcium daily, in divided doses

• Pregnancy and lactation: As advised by a physician

• Elderly patients: Dose adjusted according to calcium requirement and tolerance

A-Cal Tablet 500 mg should preferably be taken with meals to enhance absorption. Duration of therapy should be determined by a healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Calcium may reduce the absorption of certain medications such as tetracyclines, quinolones, bisphosphonates, and iron preparations. A time interval of at least 2 hours is recommended between calcium and these medicines.

Contraindications

A-Cal Tablet 500 mg is contraindicated in patients with:

• Hypercalcemia

• Hyperparathyroidism

• Severe renal impairment

• Renal calculi (kidney stones)

Side Effects

Calcium Carbonate is generally well tolerated. Some patients may experience mild gastrointestinal effects such as constipation, bloating, nausea, or abdominal discomfort, especially with high doses.

Pregnancy and Lactation

A-Cal Tablet 500 mg is safe for use during pregnancy and lactation when taken at recommended doses, as calcium is essential for fetal bone development and maternal bone health.

Storage Conditions

Store in a cool, dry place below 30°C. Protect from moisture and keep out of reach of children.