A-Phenicol Eye Drop 0.50% contains Chloramphenicol, a broad-spectrum antibiotic used in the treatment of bacterial infections of the eye. It is widely prescribed for its effectiveness against a variety of Gram-positive and Gram-negative bacteria commonly responsible for external ocular infections. The ophthalmic solution is formulated for topical use in the eye, ensuring direct delivery of the active ingredient to the site of infection for rapid and effective action.

A-Phenicol Eye Drop is commonly used in both adults and children under medical supervision. Its well-established efficacy and tolerability make it a reliable choice for managing common bacterial eye conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each milliliter of eye drop contains:

• Chloramphenicol BP 5 mg
  (Equivalent to 0.50% w/v)

Therapeutic Class

• Ophthalmic antibiotic

• Broad-spectrum antibacterial agent

Indications

A-Phenicol Eye Drop 0.50% is indicated for the treatment of bacterial infections of the eye caused by chloramphenicol-sensitive organisms, including:

External Ocular Infections

• Bacterial conjunctivitis

• Blepharitis

• Blepharoconjunctivitis

Other Eye Infections

• Superficial eye infections involving the conjunctiva or cornea

• Secondary bacterial infections of the eye

The medication is effective against common pathogens such as Staphylococcus, Streptococcus, Haemophilus influenzae, and Neisseria species. Use should be based on clinical evaluation and, where possible, bacteriological evidence.

Mechanism of Action

Chloramphenicol acts by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, preventing the formation of peptide bonds and thereby stopping bacterial growth and replication.

By interfering with protein synthesis, Chloramphenicol effectively controls the spread of infection and allows the body’s immune system to eliminate the bacteria. Its broad-spectrum activity makes A-Phenicol Eye Drop suitable for treating mixed or unidentified bacterial eye infections.

Dosage and Administration

A-Phenicol Eye Drop 0.50% should be used exactly as prescribed by a healthcare professional. The usual practice involves instilling the recommended number of drops into the affected eye(s) at specified intervals.

Before application, hands should be washed thoroughly. Care should be taken to avoid touching the dropper tip to the eye or surrounding surfaces to prevent contamination. Treatment should be continued for the full prescribed duration, even if symptoms improve earlier, to ensure complete eradication of the infection.

Precautions and Warnings

• Not recommended for patients with known hypersensitivity to Chloramphenicol.

• Prolonged or repeated use may increase the risk of secondary infections caused by non-susceptible organisms.

• Use with caution in patients with a history of blood disorders, as rare systemic effects have been reported with prolonged use.

• Contact lenses should generally be avoided during treatment unless advised otherwise by a healthcare professional.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

A-Phenicol Eye Drop is generally well tolerated. Possible side effects may include:

• Mild eye irritation or burning sensation

• Temporary blurred vision after application

• Allergic reactions such as redness or itching

If severe irritation, persistent symptoms, or signs of hypersensitivity occur, discontinue use and seek medical advice promptly.

Storage Conditions

Store in a cool, dry place below 25°C. Protect from light. Do not use the bottle beyond the recommended period after opening. Keep out of reach of children.