Abetis Plus Tablet 20 mg is a combination antihypertensive medication containing Olmesartan Medoxomil and Hydrochlorothiazide. This dual-action formula is designed to effectively manage high blood pressure (hypertension) by combining an angiotensin II receptor blocker (Olmesartan) with a thiazide diuretic (Hydrochlorothiazide). Olmesartan relaxes blood vessels, while Hydrochlorothiazide helps eliminate excess salt and water from the body. Together, they provide enhanced blood pressure control and reduce the risk of cardiovascular complications such as stroke, heart attack, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Abetis Plus Tablet 20 mg is indicated for:

• Treatment of hypertension in adults
• Patients who require combination therapy for better blood pressure management
• Reduction of cardiovascular risks associated with uncontrolled hypertension

It is particularly useful for patients whose blood pressure is not adequately controlled with a single antihypertensive agent.

Mechanism of Action

• Olmesartan Medoxomil selectively blocks angiotensin II type 1 (AT1) receptors, preventing blood vessel constriction and promoting vasodilation, which lowers blood pressure.
• Hydrochlorothiazide is a thiazide diuretic that increases the excretion of sodium and water by the kidneys, reducing blood volume and helping further decrease blood pressure.

The combination provides complementary mechanisms to achieve effective and sustained blood pressure reduction.

Dosage and Administration

• The recommended dose is one tablet once daily or as directed by a physician.
• It can be taken with or without food.
• Swallow the tablet whole with water; do not crush or chew.
• Take at the same time each day for consistent therapeutic effect.

Dosage adjustments may be required based on patient response, kidney function, and blood pressure readings.

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Headache
• Fatigue
• Increased urination
• Mild gastrointestinal discomfort

Serious but less common side effects include:

• Severe hypotension
• Electrolyte imbalances (low potassium, sodium, or magnesium)
• Kidney function impairment
• Allergic reactions

Seek immediate medical attention if serious side effects occur.

Precautions and Warnings

• Monitor blood pressure, kidney function, and electrolyte levels regularly.
• Use cautiously in patients with kidney or liver disease.
• Not recommended during pregnancy due to potential risk to the fetus.
• Avoid potassium supplements or potassium-containing salt substitutes unless advised by a physician.
• Inform your doctor about any other medications or health conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Abetis Plus Tablet may interact with:

• Other antihypertensive medications (may increase hypotensive effects)
• Potassium-sparing diuretics or potassium supplements
• NSAIDs (may reduce antihypertensive effect)
• Lithium (risk of toxicity)

Always inform your healthcare provider about all medicines you are taking.

Storage Instructions

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.