Aclobet Ointment 0.05% contains Clobetasol Propionate, a highly potent topical corticosteroid used for the short-term treatment of severe inflammatory and pruritic skin conditions. It is specifically formulated to provide rapid relief from redness, swelling, itching, and discomfort associated with various dermatological disorders that do not respond adequately to milder corticosteroids.

The ointment base allows better penetration of the active ingredient into the skin, making Aclobet Ointment 0.05% particularly suitable for thick, dry, or scaly lesions. Due to its high potency, this medicine should be used strictly under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each gram of ointment contains:

• Clobetasol Propionate BP 0.05% w/w

Therapeutic Class

• Topical corticosteroid

• Super-potent (Class I) steroid

Indications

Aclobet Ointment 0.05% is indicated for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, including:

Inflammatory Skin Disorders

• Psoriasis (excluding widespread plaque psoriasis)

• Eczema and chronic dermatitis

• Lichen planus

• Lichen simplex chronicus

Allergic and Autoimmune Conditions

• Contact dermatitis

• Atopic dermatitis (short-term use)

• Discoid lupus erythematosus

Other Corticosteroid-Responsive Conditions

• Severe insect bite reactions

• Resistant inflammatory skin conditions unresponsive to lower-potency steroids

Mechanism of Action

Clobetasol Propionate acts by suppressing the release of inflammatory mediators such as prostaglandins and leukotrienes. It inhibits inflammatory cell migration and reduces capillary permeability, leading to decreased redness, swelling, and itching.

Aclobet Ointment 0.05% also exerts vasoconstrictive and immunosuppressive effects on the skin, helping to control excessive inflammatory and immune responses that contribute to chronic and severe dermatological conditions.

Dosage and Administration

Aclobet Ointment 0.05% should be applied as a thin layer to the affected area once or twice daily, as prescribed by a healthcare professional. The ointment should be gently rubbed into the skin until absorbed.

Treatment duration is usually limited to short periods, typically not exceeding two weeks, to minimize the risk of adverse effects. Occlusive dressings should only be used if specifically advised by a physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• For external use only. Avoid contact with eyes, mouth, and mucous membranes.

• Not recommended for use on the face, groin, or axilla unless directed by a physician.

• Prolonged use may cause skin thinning, stretch marks, or systemic absorption.

• Use with caution in children, as they are more susceptible to corticosteroid-related side effects.

• Discontinue gradually as advised by a healthcare provider to avoid rebound symptoms.

Possible Side Effects

Common side effects may include:

• Burning or stinging sensation at the application site

• Skin dryness or irritation

Rare but serious side effects with prolonged or improper use include skin atrophy, pigmentation changes, and secondary infections.

Storage Conditions

Store below 25°C in a cool, dry place. Keep the tube tightly closed and away from direct sunlight. Keep out of reach of children.