Admira Tablet 80 mg contains Gliclazide 80 mg, an oral antidiabetic medication used for the management of type 2 diabetes mellitus. Gliclazide belongs to the sulfonylurea class of medicines, which lower blood sugar levels by stimulating insulin secretion from the pancreas. Admira 80 mg is prescribed for patients whose blood glucose levels are not adequately controlled with diet, exercise, and lifestyle modifications alone.
Type 2 diabetes is characterized by insufficient insulin secretion and insulin resistance, leading to chronic hyperglycemia. Admira helps restore glucose balance by increasing the body’s natural insulin production and improving overall glycemic control. It is suitable for use as monotherapy or in combination with other antidiabetic agents when required.
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Gliclazide 80 mg
Gliclazide, the active ingredient in Admira, works by stimulating pancreatic beta cells to release insulin. It binds to specific sulfonylurea receptors on beta cells, enhancing insulin secretion in response to blood glucose levels.
The therapeutic effects include:
Reduction of fasting blood glucose levels
Control of postprandial (after-meal) glucose spikes
Improvement in long-term glycemic control, reflected by reduced HbA1c levels
Additionally, Gliclazide may have cardiovascular protective effects by improving blood vessel function and reducing platelet aggregation, which can be beneficial for patients with diabetes at risk of cardiovascular disease.
Admira Tablet 80 mg is indicated for:
Management of Type 2 Diabetes Mellitus
Patients inadequately controlled with diet and exercise alone
Monotherapy in suitable patients
Combination therapy with metformin or insulin when additional glycemic control is required
Effective Blood Sugar Control: Helps reduce fasting and postprandial glucose levels
Improves HbA1c: Supports long-term glycemic management
Cardiovascular Safety: May provide protective benefits to blood vessels
Once-Daily Extended-Release Option: Enhances treatment adherence and convenience
Flexible Combination Therapy: Can be combined with other antidiabetic agents under medical supervision
The usual starting dose of Admira Tablet 80 mg is once daily, preferably with breakfast or the first main meal of the day. The dosage may be adjusted by a healthcare professional based on individual blood glucose response and patient tolerance.
Patients should not skip meals, as this increases the risk of hypoglycemia. Regular monitoring of blood glucose is essential to ensure optimal dosing and treatment outcomes.
Risk of hypoglycemia, particularly if meals are skipped, delayed, or if excessive physical activity occurs
Use with caution in elderly patients and those with kidney or liver impairment
Symptoms of low blood sugar may include sweating, tremors, dizziness, confusion, or palpitations
Mild weight gain may occur in some patients
Not suitable for patients with Type 1 diabetes or diabetic ketoacidosis
Patients should inform their healthcare provider about all medications and existing medical conditions before starting Admira Tablet 80 mg. Proper medical supervision and routine follow-up are essential for safe and effective diabetes management.
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