Clonipres ER Tablet 0.1 mg contains Clonidine Hydrochloride in an extended-release (ER) formulation. It is an antihypertensive medicine used for the management of high blood pressure (hypertension) by providing a controlled and sustained release of the active ingredient over time.

Clonidine acts on the central nervous system to reduce sympathetic nerve activity, leading to relaxation of blood vessels, decreased heart rate, and a gradual reduction in blood pressure. The ER formulation helps maintain more stable blood levels, improving 24-hour blood pressure control and reducing fluctuations compared to immediate-release forms.

Clonipres ER Tablet is used as part of long-term hypertension management, often when consistent blood pressure control is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Helps in effective long-term blood pressure control
• Provides sustained release for stable action
• Reduces sympathetic nervous system activity
• Lowers risk of hypertension-related complications
• Suitable for once-daily dosing convenience

Indications

Clonipres ER Tablet 0.1 mg is indicated for:

• Hypertension (high blood pressure)
• Resistant or difficult-to-control hypertension (as prescribed)
• Conditions requiring steady reduction of sympathetic activity

Mechanism of Action

Clonidine Hydrochloride is a centrally acting alpha-2 adrenergic agonist. It works by:

• Stimulating alpha-2 receptors in the brainstem
• Reducing sympathetic nerve outflow
• Decreasing peripheral vascular resistance and heart rate
• Leading to a sustained reduction in blood pressure

The extended-release formulation ensures gradual release of the drug, providing smoother and longer-lasting control.

Dosage & Administration

• Dosage should be taken strictly as prescribed by a physician
• Usually administered once daily
• Swallow the tablet whole; do not crush or chew
• Take at the same time each day for best results
• Do not discontinue abruptly without medical advice

Possible Side Effects

Common side effects may include:

• Drowsiness or sedation
• Dry mouth
• Dizziness
• Fatigue
• Constipation

Serious but rare side effects:

• Low blood pressure (hypotension)
• Slow heart rate (bradycardia)
• Mood changes or depression
• Rebound hypertension if stopped suddenly

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Do not stop treatment suddenly without physician guidance
• Use cautiously in patients with heart, kidney, or liver conditions
• May cause drowsiness; avoid driving if affected
• Avoid alcohol during treatment
• Regular blood pressure monitoring is recommended

Storage Instructions

• Store below 30°C in a dry place
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children.