Tetrazin Tablet 25 mg contains Tetrabenazine, a centrally acting medication used to manage hyperkinetic movement disorders. It is particularly effective in controlling chorea associated with Huntington’s disease and other neurological conditions characterized by involuntary movements. By modulating neurotransmitter activity in the brain, Tetrazin helps improve motor control and overall patient functioning.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tetrazin Tablet 25 mg is indicated for:

• Chorea associated with Huntington’s disease
• Hyperkinetic movement disorders
• Tardive dyskinesia (as advised by a physician)
• Other involuntary movement disorders

Mechanism of Action

Tetrabenazine acts by inhibiting vesicular monoamine transporter type 2 (VMAT2), which leads to depletion of monoamines such as dopamine, serotonin, and norepinephrine in nerve terminals. This results in:

• Reduction in excessive dopamine activity
• Decrease in abnormal involuntary movements
• Improved motor stability and control

Dosage and Administration

• The dosage should be individualized based on patient response and tolerability.
• Typically, treatment is started at a lower dose and gradually increased.
• The 25 mg strength may be used as part of a divided daily dose regimen.
• Take the tablet with food to minimize gastrointestinal discomfort.
• Always follow the physician’s prescription and do not abruptly discontinue therapy.

Benefits

• Effective control of chorea and involuntary movements
• Improves quality of life in patients with neurological disorders
• Flexible dosing for tailored treatment
• Helps enhance daily functional ability

Side Effects

Common side effects include:

• Drowsiness or sedation
• Fatigue
• Depression or mood changes
• Insomnia
• Nausea

Serious side effects may include:

• Severe depression or suicidal ideation
• Parkinsonism (tremors, rigidity)
• QT prolongation and cardiac rhythm disturbances

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Contraindicated in patients with untreated or severe depression
• Monitor closely for mood changes and suicidal thoughts
• Use cautiously in patients with liver impairment
• Avoid alcohol and central nervous system depressants
• Not recommended during pregnancy or breastfeeding unless clearly necessary
• Regular monitoring and follow-up are essential

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tetrazin Tablet 25 mg may interact with:

• Monoamine oxidase inhibitors (MAOIs)
• Antidepressants and antipsychotics
• Sedatives and CNS depressants
• Medications affecting cardiac rhythm

Always inform your healthcare provider about all medications you are taking.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.