Amantril Capsule 100 mg contains Amantadine Hydrochloride, an antiviral and antiparkinsonian medication used to treat and manage symptoms of Parkinson’s disease and certain viral infections. It is also effective in reducing drug-induced movement disorders caused by antipsychotic medications. This medicine works by improving nerve signaling in the brain and helping restore balance in movement control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Amantadine Hydrochloride 100 mg

Mechanism of Action

Amantadine acts through multiple mechanisms depending on the condition being treated:

• In Parkinson’s disease, it increases the release of dopamine and blocks its reuptake, thereby improving motor function and reducing symptoms such as tremors, stiffness, and slowness of movement.
• It also has NMDA receptor antagonist activity, which helps reduce abnormal brain signaling involved in movement disorders.
• As an antiviral agent, it inhibits the replication of certain viruses (notably influenza A) by interfering with viral uncoating, although its antiviral use is now limited due to resistance.

Indications

Amantril Capsule 100 mg is indicated for:

• Parkinson’s disease
• Drug-induced extrapyramidal symptoms (movement disorders)
• Management of rigidity, tremor, and bradykinesia
• Prophylaxis and treatment of influenza A (limited use)

Dosage and Administration

• The usual adult dose is 100 mg once or twice daily, depending on the condition.
• It is best taken after meals to reduce gastrointestinal discomfort.
• Dosage may need adjustment in elderly patients or those with kidney impairment.
• Do not abruptly stop the medication without consulting a doctor.

Benefits

• Improves motor control in Parkinson’s disease
• Reduces stiffness, tremors, and movement difficulties
• Helps manage drug-induced movement side effects
• Provides symptomatic relief and enhances quality of life
• Convenient oral capsule form

Possible Side Effects

Some patients may experience side effects, including:

• Dizziness or lightheadedness
• Dry mouth
• Nausea
• Insomnia
• Nervousness or confusion (especially in elderly patients)
• Blurred vision

Rare but serious effects may include hallucinations, swelling of legs, or irregular heartbeat. Seek medical advice if severe symptoms occur.

Precautions and Warnings

• Use cautiously in patients with kidney disease, heart conditions, or a history of seizures.
• Elderly patients may be more sensitive to side effects.
• Avoid alcohol, as it may increase dizziness and confusion.
• Not recommended during pregnancy or breastfeeding unless prescribed.
• Gradual dose reduction is recommended to avoid withdrawal symptoms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Amantril Capsule may interact with:

• Anticholinergic drugs
• CNS stimulants
• Diuretics (may affect drug clearance)
• Other medications affecting the central nervous system

Always inform your healthcare provider about all medicines you are taking.

Storage Instructions

• Store below 25°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.