Atasin EZ Tablet 20 mg+10 mg is a combination lipid-lowering medication containing Atorvastatin 20 mg and Ezetimibe 10 mg. This powerful duo works together to control high cholesterol levels more effectively than either drug alone. While Atorvastatin reduces cholesterol production in the liver, Ezetimibe decreases intestinal absorption of cholesterol, resulting in significant reductions in LDL (“bad”) cholesterol and triglycerides, and an increase in HDL (“good”) cholesterol.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Atorvastatin: 20 mg – a statin that reduces cholesterol synthesis in the liver
• Ezetimibe: 10 mg – inhibits intestinal absorption of cholesterol

Mechanism of Action

• Atorvastatin: Inhibits HMG-CoA reductase, lowering LDL cholesterol and total cholesterol
• Ezetimibe: Blocks cholesterol absorption in the small intestine, further reducing LDL levels
• The combination provides enhanced lipid-lowering effect, helping to prevent cardiovascular complications

Indications

Atasin EZ Tablet 20 mg+10 mg is indicated for:

• Primary hypercholesterolemia and mixed dyslipidemia
• Patients who require intensive LDL cholesterol reduction
• Familial hypercholesterolemia in combination with diet and lifestyle measures
• Prevention of heart attack, stroke, and atherosclerosis in high-risk patients
• Adjunct therapy for patients not achieving target cholesterol levels with statin alone

Dosage and Administration

• Adults: 1 tablet once daily, preferably at the same time each day
• Can be taken with or without food
• Dose adjustments may be required in patients with liver or kidney impairment
• Should be used alongside a cholesterol-lowering diet, exercise, and lifestyle modifications
• Regular monitoring of cholesterol levels and liver function is recommended

Benefits

• Significantly lowers LDL cholesterol and total cholesterol
• Reduces triglycerides and increases HDL cholesterol
• Dual mechanism provides enhanced cardiovascular protection
• Helps prevent heart attacks, stroke, and atherosclerosis
• Convenient once-daily oral tablet

Possible Side Effects

Common side effects:

• Headache
• Mild gastrointestinal disturbances (nausea, constipation, diarrhea)
• Muscle aches or mild myalgia

Rare but serious side effects:

• Severe muscle pain or weakness (myopathy/rhabdomyolysis)
• Liver enzyme elevation
• Allergic reactions such as rash, swelling, or itching

Precautions and Warnings

• Use cautiously in patients with liver disease, kidney impairment, or muscle disorders
• Avoid excessive alcohol consumption
• Not recommended during pregnancy or breastfeeding
• Inform your doctor about all medications to prevent interactions
• Regular liver function tests are advised during therapy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• CYP3A4 inhibitors (certain antifungals, antivirals, antibiotics) may increase Atorvastatin levels
• Concurrent use with other statins or lipid-lowering medications increases risk of muscle-related side effects
• Medications affecting liver or kidney function may require monitoring

Storage Instructions

• Store below 30°C in a cool, dry place
• Keep in original packaging, protected from light and moisture
• Keep out of reach of children