Avenac 100 mg is a non-steroidal anti-inflammatory drug (NSAID) indicated for the relief of pain and inflammation associated with various musculoskeletal and inflammatory conditions. Its potent anti-inflammatory and analgesic properties make it effective for managing symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma, and lumbago.

Avenac works by inhibiting cyclooxygenase (COX), the enzyme responsible for producing prostaglandins, which are mediators of pain, inflammation, and fever. Rapid oral absorption ensures effective relief, allowing patients to maintain daily activities with reduced discomfort.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Drugs for Osteoarthritis

• Drugs used for Rheumatoid Arthritis

• Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Pharmacology

Avenac 100 mg is a selective COX inhibitor. By reducing prostaglandin synthesis, it decreases inflammation, swelling, pain, and stiffness in affected joints or tissues. After oral administration, the drug is rapidly and completely absorbed in an unchanged form, providing quick symptomatic relief.

Indications

Avenac 100 mg is indicated for:

• Relief of pain and inflammation in osteoarthritis

• Management of rheumatoid arthritis

• Treatment of ankylosing spondylitis

• Relief of toothache and trauma-related pain

• Management of lumbago and musculoskeletal discomfort

Dosage and Administration

Extended-release tablet:

• Adults: One 200 mg tablet daily, or as prescribed by the physician

Film-coated tablet:

• Adults: 100 mg twice daily

Dosage should be individualized based on the patient’s condition, severity of symptoms, and response to therapy. Tablets should be taken orally with water, preferably after meals to minimize gastrointestinal irritation.

Drug Interactions

Although no significant interactions have been reported, caution is advised when used with:

• Lithium and Digoxin: May increase plasma concentrations

• Diuretics: May alter effectiveness

• Anticoagulants: May enhance anticoagulant effect

• Methotrexate: May increase plasma levels

Close monitoring is recommended when co-administered with these medications.

Contraindications

• Known hypersensitivity to Avenac or other NSAIDs

• History of aspirin- or NSAID-induced asthma

• Active gastrointestinal bleeding or peptic ulcer

Side Effects

Avenac 100 mg is generally well tolerated. Potential side effects include:

• Gastrointestinal disturbances: nausea, dyspepsia, abdominal discomfort

• Headache or dizziness

• Rarely: hypersensitivity reactions such as urticaria or rash

Prolonged use may increase the risk of gastrointestinal bleeding or kidney impairment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with peptic ulcer, gastrointestinal bleeding, moderate-to-severe hepatic, cardiac, or renal impairment

• Monitor patients prone to dizziness or allergic reactions

• Avoid long-term use unless necessary and under supervision

Pregnancy and Lactation

Use of Avenac 100 mg is not recommended during pregnancy or lactation unless the potential benefits outweigh the risks to the mother and fetus.

Use in Special Populations

• Pediatrics: No clinical data available; use not recommended in children

• Elderly: Use with caution due to increased risk of gastrointestinal or renal complications

Storage Conditions

Store in a dry place, protected from light and heat, at room temperature. Keep out of reach of children.