Avidro Tablet 1.5 mg contains Pizotifen, a serotonin antagonist with antihistaminic properties, primarily used for the prophylactic treatment of migraine. Unlike medicines used to treat an acute migraine attack, Avidro is taken regularly to reduce the frequency, severity, and duration of migraine episodes, helping patients achieve better long-term control of their condition.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Indication

Avidro Tablet 1.5 mg is indicated for:

• Prophylaxis of migraine headaches

• Prevention of recurrent migraine attacks

• Management of chronic or frequent migraines

It is not intended for the relief of an ongoing migraine attack but for long-term prevention under medical supervision.

Mechanism of Action

Pizotifen works mainly by blocking serotonin (5-HT₂) receptors in the brain. Serotonin plays a key role in the development of migraine by influencing blood vessel constriction and dilation in the brain. By antagonizing serotonin receptors, Pizotifen:

• Prevents abnormal blood vessel changes associated with migraine

• Reduces neuronal hypersensitivity

• Lowers the likelihood of migraine initiation

Its mild antihistaminic and anticholinergic effects may also contribute to its preventive action.

Dosage and Administration

• The dosage is individualized based on patient response and tolerance.

• Avidro Tablet 1.5 mg is usually taken once daily, often in the evening, or as prescribed by a physician.

• Tablets should be swallowed whole with water.

Treatment is typically started at a low dose and gradually increased to minimize side effects.

Benefits and Features

• Helps reduce the frequency and intensity of migraine attacks

• Suitable for long-term migraine prevention

• Improves quality of life in patients with recurrent migraines

• Simple once-daily dosing enhances treatment adherence

• Well established migraine prophylactic agent

Use in Special Populations

• Elderly patients: Use with caution and dose adjustment if necessary

• Children: Use only under specialist advice

• Pregnancy and breastfeeding: Use only if clearly indicated and prescribed by a healthcare professional

Precautions and Warnings

Avidro Tablet 1.5 mg should be used cautiously in patients with:

• History of glaucoma

• Urinary retention

• Epilepsy

• Cardiovascular disease

Patients should be advised about the possibility of increased appetite and drowsiness, especially during the initial phase of treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Some patients may experience:

• Increased appetite and weight gain

• Drowsiness or sedation

• Dry mouth

• Dizziness

• Fatigue

These side effects are often dose-related and may lessen with continued use or dose adjustment.

Storage Conditions

• Store in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Conclusion

Avidro Tablet 1.5 mg (Pizotifen) is an effective preventive therapy for patients suffering from frequent or severe migraine attacks. By reducing migraine frequency and improving long-term symptom control, it plays a valuable role in migraine prophylaxis and helps enhance patients’ daily functioning and overall quality of life.