Avloclav BID Suspension is a broad-spectrum oral antibiotic containing Amoxicillin 400 mg and Clavulanic Acid 57.5 mg per 5 ml. This formulation is specifically designed for twice-daily dosing (BID), providing convenience and consistent antibacterial coverage. The combination is effective against beta-lactamase-producing bacteria that are resistant to amoxicillin alone. Amoxicillin works by disrupting bacterial cell wall synthesis, while Clavulanic Acid protects amoxicillin from enzymatic degradation, enhancing its efficacy. This suspension is suitable for children and adults who have difficulty swallowing tablets.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amoxicillin: 400 mg – penicillin-type antibiotic that inhibits bacterial cell wall synthesis
• Clavulanic Acid: 57.5 mg – beta-lactamase inhibitor that prevents enzymatic breakdown of amoxicillin

Mechanism of Action

• Amoxicillin: Binds to bacterial penicillin-binding proteins (PBPs), inhibiting cell wall synthesis, resulting in bacterial death
• Clavulanic Acid: Blocks beta-lactamase enzymes, allowing amoxicillin to remain effective against resistant bacteria
• Provides enhanced antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria

Indications

Avloclav BID Suspension is indicated for the treatment of:

• Respiratory tract infections: bronchitis, pneumonia, sinusitis
• Ear, nose, and throat infections: otitis media, tonsillitis, pharyngitis
• Urinary tract infections
• Skin and soft tissue infections: cellulitis, abscesses, wound infections
• Dental infections and other mild to moderate bacterial infections

Dosage and Administration

• Shake the bottle well before use to ensure uniform suspension
• Use the measuring cup or syringe provided for accurate dosing
• Typical pediatric dose: 20–40 mg/kg/day (based on amoxicillin component) divided into 2 doses every 12 hours
• Administer as prescribed by the physician
• Complete the full course of therapy, even if symptoms improve early

Benefits

• Effective against resistant bacterial strains
• Twice-daily dosing (BID) improves compliance
• Pediatric-friendly oral suspension for easy administration
• Treats respiratory, urinary, skin, and dental infections
• Reduces risk of treatment failure due to beta-lactamase-producing bacteria

Possible Side Effects

Common side effects:

• Diarrhea or loose stools
• Nausea and vomiting
• Mild rash or itching

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, swelling, difficulty breathing)
• Liver enzyme abnormalities or jaundice
• Clostridium difficile-associated diarrhea

Precautions and Warnings

• Contraindicated in patients with penicillin allergy
• Use cautiously in patients with renal impairment
• Monitor for allergic reactions or severe gastrointestinal symptoms
• Not effective against viral infections
• Inform your physician of all other medications being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants, methotrexate, allopurinol, and other antibiotics
• May reduce effectiveness of oral contraceptives
• Dose adjustment may be required in renal impairment

Storage Instructions

• Store at 15–25°C, protected from light and moisture
• Shake well before each use
• Keep out of reach of children
• Discard remaining suspension after expiry date.