Prelizer Tablet 2.5 mg contains Bisoprolol Fumarate, a cardioselective beta-1 adrenergic receptor blocker (beta-blocker). It is primarily used to treat high blood pressure (hypertension), chronic stable angina, and chronic heart failure.

Bisoprolol works by slowing the heart rate and reducing the force of contraction, which decreases the heart’s workload and oxygen demand. The 2.5 mg strength is often used as a starting dose, especially in heart failure patients or individuals requiring gradual dose titration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Prelizer 2.5 mg is indicated for:

• Hypertension (high blood pressure)

• Chronic stable angina (chest pain due to coronary artery disease)

• Chronic heart failure (as part of combination therapy)

Controlling blood pressure and heart rate helps reduce the risk of heart attack, stroke, and other cardiovascular complications.

Dosage and Administration

• The usual starting dose for heart failure is 1.25 mg to 2.5 mg once daily, gradually increased as tolerated.

• For hypertension or angina, dosing is determined by the physician.

• Take once daily, preferably in the morning.

• Swallow the tablet with water, with or without food.

Do not stop the medication abruptly, as sudden discontinuation may worsen heart conditions. Taper gradually under medical supervision.

Mechanism of Action

Bisoprolol selectively blocks beta-1 receptors in the heart. This results in:

• Reduced heart rate

• Decreased cardiac output

• Lower blood pressure

• Reduced myocardial oxygen demand

Its cardioselective action means it has less effect on beta-2 receptors in the lungs compared to non-selective beta-blockers.

Benefits

• Effective blood pressure control

• Reduces angina symptoms

• Improves survival in chronic heart failure (when used appropriately)

• Once-daily dosing

• Generally well tolerated

Safety Information

Contraindications

• Severe bradycardia (slow heart rate)

• Cardiogenic shock

• Severe asthma or bronchospasm (use cautiously)

• Second or third-degree heart block (without pacemaker)

• Hypersensitivity to bisoprolol

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Warnings and Precautions

• Monitor heart rate and blood pressure regularly

• Use cautiously in diabetic patients (may mask hypoglycemia symptoms)

• Caution in patients with respiratory disorders

• Avoid abrupt discontinuation

Common Side Effects

• Fatigue

• Dizziness

• Slow heart rate

• Cold extremities

• Mild gastrointestinal discomfort

Seek medical attention if severe dizziness, fainting, breathing difficulty, or very slow heartbeat occurs.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.