Aciflox Tablet 200 mg contains Sparfloxacin, a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and cell division, effectively killing the bacteria and stopping the spread of infection. Aciflox is prescribed for infections of the respiratory tract, urinary tract, skin, and soft tissues, and is particularly useful for strains resistant to other antibiotics.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Aciflox Tablet 200 mg is indicated for the treatment of:

• Respiratory tract infections, including bronchitis and pneumonia
• Urinary tract infections
• Skin and soft tissue infections
• Ear, nose, and throat infections, including sinusitis
• Certain gastrointestinal infections caused by susceptible bacteria

Mechanism of Action

Sparfloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes responsible for DNA replication, transcription, and repair. By disrupting these essential processes, the drug prevents bacterial proliferation and effectively eliminates the infection. Its broad-spectrum activity makes it effective against both Gram-positive and Gram-negative bacteria.

Dosage and Administration

• Adults: 200 mg once or twice daily, depending on the severity of infection and physician’s recommendation.
• Swallow the tablet whole with water, preferably on an empty stomach for optimal absorption.
• Complete the full course of therapy even if symptoms improve to prevent resistance.
• Dosage adjustment may be required in patients with renal impairment.

Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea
• Dizziness or headache
• Mild skin rash or itching

Rare but serious side effects include:

• Tendon inflammation or rupture (especially in elderly patients)
• Severe allergic reactions
• Photosensitivity (increased sensitivity to sunlight)
• Liver enzyme abnormalities

Seek immediate medical attention if severe reactions occur.

Precautions and Warnings

• Use with caution in elderly patients and those with kidney or liver impairment.
• Avoid exposure to direct sunlight or UV light while taking this medication.
• Inform your doctor if you have a history of tendon disorders or muscle weakness.
• Not recommended during pregnancy or breastfeeding unless prescribed by a physician.
• Monitor for signs of allergic reactions, tendon pain, or unusual muscle weakness during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Aciflox Tablet may interact with:

• Antacids containing magnesium or aluminum – may reduce absorption
• Warfarin – may enhance anticoagulant effect
• Other QT-prolonging drugs – may increase risk of heart rhythm disturbances
• Nonsteroidal anti-inflammatory drugs (NSAIDs) – may increase CNS side effects

Inform your physician about all medications being taken.

Storage Instructions

• Store in a cool, dry place below 25°C
• Protect from light and moisture
• Keep out of reach of children.