Aximin Tablet 550 mg contains Rifaximin, a broad-spectrum, gut-selective antibiotic used for the treatment and prevention of various gastrointestinal disorders caused by bacterial overgrowth or infection. Due to its minimal systemic absorption, Aximin acts locally in the gastrointestinal tract, providing effective antimicrobial action with a low risk of systemic side effects. It is commonly prescribed in conditions such as hepatic encephalopathy, irritable bowel syndrome with diarrhea, and traveler’s diarrhea.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Rifaximin

• Strength: 550 mg

• Dosage Form: Oral tablet

Therapeutic Class

• Gastrointestinal Antibiotic

• Rifamycin derivative

Indications

Aximin Tablet 550 mg is indicated for:

• Hepatic encephalopathy to reduce recurrence by lowering ammonia-producing gut bacteria

• Irritable bowel syndrome with diarrhea (IBS-D)

• Traveler’s diarrhea caused by non-invasive strains of Escherichia coli

• Management of bacterial overgrowth in the intestine, as advised by a physician

Pharmacology

Rifaximin works by inhibiting the DNA-dependent RNA polymerase enzyme in susceptible bacteria, leading to suppression of bacterial RNA synthesis and cell death. Unlike many systemic antibiotics, rifaximin is poorly absorbed from the gastrointestinal tract, allowing it to exert its action primarily within the intestinal lumen.

By selectively targeting pathogenic gut bacteria, Aximin helps restore normal intestinal flora balance, reduce toxin and ammonia production, and alleviate gastrointestinal symptoms such as diarrhea, bloating, and abdominal discomfort. Its localized action minimizes the risk of antibiotic resistance and systemic adverse effects.

Dosage and Administration

• The usual recommended dose is 550 mg two to three times daily, depending on the indication and physician’s advice.

• Tablets may be taken with or without food.

• Duration of therapy varies based on the treated condition and clinical response.

• Patients should complete the full course of treatment as prescribed.

Side Effects

Aximin Tablet is generally well tolerated. Some patients may experience:

• Nausea

• Abdominal pain or discomfort

• Flatulence

• Headache

• Dizziness

Serious side effects are rare due to minimal systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with severe hepatic impairment.

• Not recommended for diarrhea caused by invasive pathogens with fever or blood in stools unless specifically prescribed.

• Prolonged or repeated use should be under medical supervision.

• Safety during pregnancy and breastfeeding should be evaluated by a physician before use.

Drug Interactions

Rifaximin has a low potential for drug interactions. However, caution is advised when used with other antibiotics or drugs that alter gut flora. Patients taking multiple medications should inform their healthcare provider.

Storage Conditions

• Store in a cool, dry place below 30°C

• Protect from light and moisture

• Keep out of reach of children.