Axinat-F Inhaler (25 mcg + 125 mcg per puff) is a combination inhalation therapy formulated with Salmeterol and Fluticasone Propionate. It is used for the long-term management of bronchial asthma and chronic obstructive pulmonary disease (COPD) in patients who require both bronchodilation and anti-inflammatory control. This inhaler helps maintain open airways, reduce airway inflammation, and improve overall respiratory function when used regularly as prescribed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Salmeterol: 25 mcg per puff

• Fluticasone Propionate: 125 mcg per puff

• Dosage Form: Metered dose inhaler

Therapeutic Class

• Long-acting beta-2 adrenergic agonist (LABA)

• Inhaled corticosteroid

• Combination bronchodilator and anti-inflammatory agent

Indications

Axinat-F Inhaler (25 mcg + 125 mcg)/puff is indicated for:

• Maintenance treatment of bronchial asthma in patients inadequately controlled on inhaled corticosteroids alone

• Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema

• Prevention of asthma symptoms, including wheezing, chest tightness, and shortness of breath

• Reduction in the frequency and severity of asthma and COPD exacerbations

This inhaler is intended for regular, long-term use and is not suitable for the relief of acute asthma attacks.

Pharmacology

Axinat-F Inhaler provides dual therapeutic action through its two active components:

• Salmeterol is a selective long-acting beta-2 adrenergic receptor agonist that relaxes bronchial smooth muscle, resulting in prolonged bronchodilation lasting up to 12 hours. It helps prevent bronchospasm and improves airflow, making breathing easier over an extended period.

• Fluticasone Propionate is a potent inhaled corticosteroid that works locally in the lungs to reduce inflammation, swelling, and mucus production in the airways. By controlling underlying inflammation, it improves lung function and lowers the risk of asthma exacerbations.

The combination of these agents ensures effective control of both airway constriction and inflammation, which are key factors in chronic respiratory diseases.

Dosage and Administration

• The usual recommended dose is one puff twice daily, or as advised by a healthcare professional.

• The inhaler should be used at regular intervals for optimal benefit.

• Patients should be trained in correct inhalation technique to ensure proper drug delivery.

• Rinsing the mouth with water after each use is recommended to minimize oral side effects.

Side Effects

Axinat-F Inhaler is generally well tolerated. Possible side effects include:

• Headache

• Tremor

• Palpitations

• Throat irritation or hoarseness

• Oral candidiasis with prolonged use

Most side effects are mild and reduce with continued use and proper inhaler technique.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not intended for acute bronchospasm or sudden asthma attacks.

• Should be used with caution in patients with cardiovascular disorders, diabetes mellitus, or thyroid disease.

• Long-term therapy should be monitored by a physician.

• Pediatric and elderly patients may require careful supervision.

Drug Interactions

Caution is advised when used alongside beta-blockers, other long-acting bronchodilators, or strong CYP3A4 inhibitors, as these may alter the effects of salmeterol or fluticasone.

Storage Conditions

• Store below 30°C

• Protect from heat and direct sunlight

• Do not puncture or burn the canister

• Keep out of reach of children.