Bactrobex Ointment 2% w/w contains Mupirocin, a topical antibacterial agent used for the treatment of a wide range of primary and secondary bacterial skin infections. It is particularly effective against Gram-positive organisms, including Staphylococcus aureus and Streptococcus species, making it a reliable option for managing localized skin infections and preventing the spread of bacteria on damaged skin.

This ointment is formulated for external use and provides high local antibacterial activity with minimal systemic absorption, ensuring effective treatment while reducing the risk of systemic side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Mupirocin 2% w/w

Therapeutic Class

Topical antibacterial (antibiotic)

Indications

Bactrobex Ointment 2% w/w is indicated for the treatment of:

• Impetigo

• Infected cuts, wounds, and abrasions

• Folliculitis

• Secondary bacterial infections of eczema or dermatitis

• Minor skin infections caused by susceptible bacteria

Pharmacology

Mupirocin is a naturally derived antibiotic that acts by inhibiting bacterial protein synthesis. It specifically binds to bacterial isoleucyl-tRNA synthetase, an enzyme essential for protein production. This unique mechanism of action results in effective bacteriostatic or bactericidal activity, depending on drug concentration and bacterial susceptibility.

Due to its distinctive mode of action, Mupirocin shows minimal cross-resistance with other antibiotics, making it effective against strains resistant to commonly used antibacterial agents. When applied topically, systemic absorption is negligible, and any absorbed drug is rapidly metabolized to inactive monic acid.

Dosage and Administration

Bactrobex Ointment is for topical use only.

• Apply a small amount to the affected area two to three times daily, or as directed by a physician

• The treated area may be covered with a sterile dressing if required

• Treatment duration is usually up to 10 days, depending on the severity of infection

Hands should be washed before and after application to prevent contamination and spread of infection.

Contraindications

Bactrobex Ointment 2% w/w is contraindicated in patients with known hypersensitivity to Mupirocin or any component of the formulation.

Side Effects

Bactrobex Ointment is generally well tolerated. Possible side effects include:

• Burning or stinging sensation at the application site

• Itching or redness

• Dryness of skin

• Local irritation

Allergic reactions are rare but may occur. Treatment should be discontinued if severe irritation or hypersensitivity develops.

Precautions and Warnings

• Avoid contact with eyes, nose, mouth, and mucous membranes

• Prolonged use may result in overgrowth of non-susceptible organisms, including fungi

• Do not use on large areas of damaged skin unless advised by a physician

• If no clinical improvement is observed within 3–5 days, medical advice should be sought

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Pregnancy and Lactation

Bactrobex Ointment should be used during pregnancy only if clearly needed. It is not known whether Mupirocin is excreted in human milk; caution is advised when used by breastfeeding mothers, especially if applied to large skin areas.

Storage Conditions

Store below 25–30°C in a cool, dry place. Protect from light. Keep out of reach of children.

Mode of Action

Mupirocin exerts its antibacterial effect by selectively inhibiting bacterial protein synthesis, leading to the elimination of susceptible bacteria at the site of infection and promoting healing of infected skin.